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FGF-dependent metabolic control of vascular development

Author

Listed:
  • Pengchun Yu

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Kerstin Wilhelm

    (Angiogenesis & Metabolism Laboratory, Max Plank Institute for Heart and Lung Research)

  • Alexandre Dubrac

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Joe K. Tung

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Tiago C. Alves

    (Section of Endocrinology, Yale University School of Medicine)

  • Jennifer S. Fang

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Yi Xie

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Jie Zhu

    (Yale University School of Medicine)

  • Zehua Chen

    (Computational Statistics and Bioinformatics Group, Advanced Artificial Intelligence Research Laboratory, WuXi NextCODE Genomics)

  • Frederik De Smet

    (Switch Laboratory
    Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute)

  • Jiasheng Zhang

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Suk-Won Jin

    (Yale Cardiovascular Research Centre, Yale University School of Medicine
    School of Life Sciences, Gwangju Institute of Science and Technology)

  • Lele Sun

    (Genomics Laboratory, WuXi NextCODE Genomics)

  • Hongye Sun

    (Genomics Laboratory, WuXi NextCODE Genomics)

  • Richard G. Kibbey

    (Section of Endocrinology, Yale University School of Medicine)

  • Karen K. Hirschi

    (Yale Cardiovascular Research Centre, Yale University School of Medicine)

  • Nissim Hay

    (College of Medicine, University of Illinois at Chicago)

  • Peter Carmeliet

    (Laboratory of Angiogenesis and Neurovascular Link
    Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center)

  • Thomas W. Chittenden

    (Computational Statistics and Bioinformatics Group, Advanced Artificial Intelligence Research Laboratory, WuXi NextCODE Genomics)

  • Anne Eichmann

    (Yale Cardiovascular Research Centre, Yale University School of Medicine
    U970, Paris Cardiovascular Research Center)

  • Michael Potente

    (Angiogenesis & Metabolism Laboratory, Max Plank Institute for Heart and Lung Research)

  • Michael Simons

    (Yale Cardiovascular Research Centre, Yale University School of Medicine
    Yale University School of Medicine)

Abstract

Fibroblast growth factor receptor (FGFR) signalling is a crucial regulator of endothelial metabolism and vascular development.

Suggested Citation

  • Pengchun Yu & Kerstin Wilhelm & Alexandre Dubrac & Joe K. Tung & Tiago C. Alves & Jennifer S. Fang & Yi Xie & Jie Zhu & Zehua Chen & Frederik De Smet & Jiasheng Zhang & Suk-Won Jin & Lele Sun & Hongye, 2017. "FGF-dependent metabolic control of vascular development," Nature, Nature, vol. 545(7653), pages 224-228, May.
    • Handle: RePEc:nat:nature:v:545:y:2017:i:7653:d:10.1038_nature22322
    DOI: 10.1038/nature22322
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    Citations

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    Cited by:

    1. Nieves Montenegro-Navarro & Claudia García-Báez & Melissa García-Caballero, 2023. "Molecular and metabolic orchestration of the lymphatic vasculature in physiology and pathology," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
    2. Balkrishna Chaube & Kathryn M. Citrin & Mahnaz Sahraei & Abhishek K. Singh & Diego Saenz Urturi & Wen Ding & Richard W. Pierce & Raaisa Raaisa & Rebecca Cardone & Richard Kibbey & Carlos Fernández-Her, 2023. "Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis," Nature Communications, Nature, vol. 14(1), pages 1-21, December.
    3. Yuanli Zhen & Kai Liu & Lei Shi & Simran Shah & Qin Xu & Haley Ellis & Eranga R. Balasooriya & Johannes Kreuzer & Robert Morris & Albert S. Baldwin & Dejan Juric & Wilhelm Haas & Nabeel Bardeesy, 2024. "FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma," Nature Communications, Nature, vol. 15(1), pages 1-17, December.

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