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New CRISPR–Cas systems from uncultivated microbes

Author

Listed:
  • David Burstein

    (University of California)

  • Lucas B. Harrington

    (University of California)

  • Steven C. Strutt

    (University of California)

  • Alexander J. Probst

    (University of California)

  • Karthik Anantharaman

    (University of California)

  • Brian C. Thomas

    (University of California)

  • Jennifer A. Doudna

    (University of California
    University of California
    Howard Hughes Medical Institute, University of California
    Innovative Genomics Initiative, University of California)

  • Jillian F. Banfield

    (University of California
    Policy, and Management, University of California)

Abstract

Using a metagenomic approach, three types of CRISPR–Cas systems have been discovered in uncultivated bacterial and archaeal hosts from a variety of different environments.

Suggested Citation

  • David Burstein & Lucas B. Harrington & Steven C. Strutt & Alexander J. Probst & Karthik Anantharaman & Brian C. Thomas & Jennifer A. Doudna & Jillian F. Banfield, 2017. "New CRISPR–Cas systems from uncultivated microbes," Nature, Nature, vol. 542(7640), pages 237-241, February.
    • Handle: RePEc:nat:nature:v:542:y:2017:i:7640:d:10.1038_nature21059
    DOI: 10.1038/nature21059
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    Citations

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    Cited by:

    1. Daniela S. Aliaga Goltsman & Lisa M. Alexander & Jyun-Liang Lin & Rodrigo Fregoso Ocampo & Benjamin Freeman & Rebecca C. Lamothe & Andres Perez Rivas & Morayma M. Temoche-Diaz & Shailaja Chadha & Nata, 2022. "Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    2. Xiaoguang Pan & Kunli Qu & Hao Yuan & Xi Xiang & Christian Anthon & Liubov Pashkova & Xue Liang & Peng Han & Giulia I. Corsi & Fengping Xu & Ping Liu & Jiayan Zhong & Yan Zhou & Tao Ma & Hui Jiang & J, 2022. "Massively targeted evaluation of therapeutic CRISPR off-targets in cells," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    3. Changchang Xin & Jianhang Yin & Shaopeng Yuan & Liqiong Ou & Mengzhu Liu & Weiwei Zhang & Jiazhi Hu, 2022. "Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    4. Feiyu Zhao & Tao Zhang & Xiaodi Sun & Xiyun Zhang & Letong Chen & Hejun Wang & Jinze Li & Peng Fan & Liangxue Lai & Tingting Sui & Zhanjun Li, 2023. "A strategy for Cas13 miniaturization based on the structure and AlphaFold," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    5. Danielle Miller & Adi Stern & David Burstein, 2022. "Deciphering microbial gene function using natural language processing," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    6. Zongzhi Wu & Tang Liu & Qian Chen & Tianyi Chen & Jinyun Hu & Liyu Sun & Bingxue Wang & Wenpeng Li & Jinren Ni, 2024. "Unveiling the unknown viral world in groundwater," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    7. Boris Kantor & Bernadette O’Donovan & Joseph Rittiner & Dellila Hodgson & Nicholas Lindner & Sophia Guerrero & Wendy Dong & Austin Zhang & Ornit Chiba-Falek, 2024. "The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    8. Natasha K. Dudek & Jesus G. Galaz-Montoya & Handuo Shi & Megan Mayer & Cristina Danita & Arianna I. Celis & Tobias Viehboeck & Gong-Her Wu & Barry Behr & Silvia Bulgheresi & Kerwyn Casey Huang & Wah C, 2023. "Previously uncharacterized rectangular bacterial structures in the dolphin mouth," Nature Communications, Nature, vol. 14(1), pages 1-15, December.

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