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Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body

Author

Listed:
  • L. J. Worrall

    (University of British Columbia)

  • C. Hong

    (CryoEM Shared Resources, Janelia Research Campus, Howard Hughes Medical Institute)

  • M. Vuckovic

    (University of British Columbia)

  • W. Deng

    (Michael Smith Laboratories, University of British Columbia)

  • J. R. C. Bergeron

    (University of British Columbia
    †Present addresses: Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA (J.R.C.B.); Zymeworks, Vancouver, British Columbia V6H 3V9, Canada (T.S.).)

  • D. D Majewski

    (University of British Columbia)

  • R. K. Huang

    (CryoEM Shared Resources, Janelia Research Campus, Howard Hughes Medical Institute)

  • T. Spreter

    (University of British Columbia
    †Present addresses: Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA (J.R.C.B.); Zymeworks, Vancouver, British Columbia V6H 3V9, Canada (T.S.).)

  • B. B. Finlay

    (Michael Smith Laboratories, University of British Columbia)

  • Z. Yu

    (CryoEM Shared Resources, Janelia Research Campus, Howard Hughes Medical Institute)

  • N. C. J. Strynadka

    (University of British Columbia)

Abstract

The authors report the structure of the assembled membrane spanning ring forming proteins of the Salmonella Typhimurium injectisome basal body, including the first atomic structure of a member of the secretin family of outer-membrane pores.

Suggested Citation

  • L. J. Worrall & C. Hong & M. Vuckovic & W. Deng & J. R. C. Bergeron & D. D Majewski & R. K. Huang & T. Spreter & B. B. Finlay & Z. Yu & N. C. J. Strynadka, 2016. "Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body," Nature, Nature, vol. 540(7634), pages 597-601, December.
  • Handle: RePEc:nat:nature:v:540:y:2016:i:7634:d:10.1038_nature20576
    DOI: 10.1038/nature20576
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    Cited by:

    1. Rebecca Conners & Mathew McLaren & Urszula Łapińska & Kelly Sanders & M. Rhia L. Stone & Mark A. T. Blaskovich & Stefano Pagliara & Bertram Daum & Jasna Rakonjac & Vicki A. M. Gold, 2021. "CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
    2. Matteo Tassinari & Marta Rudzite & Alain Filloux & Harry H. Low, 2023. "Assembly mechanism of a Tad secretion system secretin-pilotin complex," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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