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Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

Author

Listed:
  • Gopal Sapparapu

    (Vanderbilt University Medical Center
    The Vanderbilt Vaccine Center, Vanderbilt University Medical Center)

  • Estefania Fernandez

    (Washington University School of Medicine)

  • Nurgun Kose

    (The Vanderbilt Vaccine Center, Vanderbilt University Medical Center)

  • Bin Cao

    (Washington University School of Medicine)

  • Julie M. Fox

    (Washington University School of Medicine)

  • Robin G. Bombardi

    (The Vanderbilt Vaccine Center, Vanderbilt University Medical Center)

  • Haiyan Zhao

    (Washington University School of Medicine)

  • Christopher A. Nelson

    (Washington University School of Medicine)

  • Aubrey L. Bryan

    (Integral Molecular)

  • Trevor Barnes

    (Integral Molecular)

  • Edgar Davidson

    (Integral Molecular)

  • Indira U. Mysorekar

    (Washington University School of Medicine
    Washington University School of Medicine)

  • Daved H. Fremont

    (Washington University School of Medicine)

  • Benjamin J. Doranz

    (Integral Molecular)

  • Michael S. Diamond

    (Washington University School of Medicine
    Washington University School of Medicine
    Washington University School of Medicine
    Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine)

  • James E. Crowe

    (Vanderbilt University Medical Center
    The Vanderbilt Vaccine Center, Vanderbilt University Medical Center
    Microbiology and Immunology, Vanderbilt University)

Abstract

Monoclonal Zika-virus-neutralizing human antibodies can protect against maternal–fetal transmission, infection and disease.

Suggested Citation

  • Gopal Sapparapu & Estefania Fernandez & Nurgun Kose & Bin Cao & Julie M. Fox & Robin G. Bombardi & Haiyan Zhao & Christopher A. Nelson & Aubrey L. Bryan & Trevor Barnes & Edgar Davidson & Indira U. My, 2016. "Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice," Nature, Nature, vol. 540(7633), pages 443-447, December.
    • Handle: RePEc:nat:nature:v:540:y:2016:i:7633:d:10.1038_nature20564
    DOI: 10.1038/nature20564
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    Cited by:

    1. Jimena Barbeito-Andrés & Lavínia Schuler-Faccini & Patricia Pestana Garcez, 2018. "Why is congenital Zika syndrome asymmetrically distributed among human populations?," PLOS Biology, Public Library of Science, vol. 16(8), pages 1-11, August.
    2. Xinglong Liu & Zhengfeng Li & Xiaoxia Li & Weixuan Wu & Huadong Jiang & Yufen Zheng & Junjie Zhou & Xianmiao Ye & Junnan Lu & Wei Wang & Lei Yu & Yiping Li & Linbing Qu & Jianhua Wang & Feng Li & Ling, 2024. "A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice," Nature Communications, Nature, vol. 15(1), pages 1-19, December.

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