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Microcins mediate competition among Enterobacteriaceae in the inflamed gut

Author

Listed:
  • Martina Sassone-Corsi

    (University of California Irvine
    Institute for Immunology, University of California Irvine)

  • Sean-Paul Nuccio

    (University of California Irvine
    Institute for Immunology, University of California Irvine)

  • Henry Liu

    (University of California Irvine)

  • Dulcemaria Hernandez

    (University of California Irvine)

  • Christine T. Vu

    (University of California Irvine)

  • Amy A. Takahashi

    (University of California Irvine)

  • Robert A. Edwards

    (Institute for Immunology, University of California Irvine
    University of California)

  • Manuela Raffatellu

    (University of California Irvine
    Institute for Immunology, University of California Irvine)

Abstract

Certain commensal enterobacteria secrete small proteins called microcins that suppress the growth of other bacteria in the inflamed gut, conferring an intra- and interspecies competitive advantage.

Suggested Citation

  • Martina Sassone-Corsi & Sean-Paul Nuccio & Henry Liu & Dulcemaria Hernandez & Christine T. Vu & Amy A. Takahashi & Robert A. Edwards & Manuela Raffatellu, 2016. "Microcins mediate competition among Enterobacteriaceae in the inflamed gut," Nature, Nature, vol. 540(7632), pages 280-283, December.
  • Handle: RePEc:nat:nature:v:540:y:2016:i:7632:d:10.1038_nature20557
    DOI: 10.1038/nature20557
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    Cited by:

    1. Judith Behnsen & Hui Zhi & Allegra T. Aron & Vivekanandan Subramanian & William Santus & Michael H. Lee & Romana R. Gerner & Daniel Petras & Janet Z. Liu & Keith D. Green & Sarah L. Price & Jose Camac, 2021. "Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
    2. Ana Djukovic & María José Garzón & Cécile Canlet & Vitor Cabral & Rym Lalaoui & Marc García-Garcerá & Julia Rechenberger & Marie Tremblay-Franco & Iván Peñaranda & Leonor Puchades-Carrasco & Antonio P, 2022. "Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    3. Yiqian Duan & Célio Dias Santos-Júnior & Thomas Sebastian Schmidt & Anthony Fullam & Breno L. S. Almeida & Chengkai Zhu & Michael Kuhn & Xing-Ming Zhao & Peer Bork & Luis Pedro Coelho, 2024. "A catalog of small proteins from the global microbiome," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

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