IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v538y2016i7624d10.1038_nature19789.html
   My bibliography  Save this article

A cholinergic basal forebrain feeding circuit modulates appetite suppression

Author

Listed:
  • Alexander M. Herman

    (Program in Developmental Biology, Baylor College of Medicine)

  • Joshua Ortiz-Guzman

    (Program in Developmental Biology, Baylor College of Medicine)

  • Mikhail Kochukov

    (Baylor College of Medicine)

  • Isabella Herman

    (Program in Developmental Biology, Baylor College of Medicine
    Medical Scientist Training Program, Baylor College of Medicine)

  • Kathleen B. Quast

    (Baylor College of Medicine)

  • Jay M. Patel

    (Medical Scientist Training Program, Baylor College of Medicine
    Baylor College of Medicine)

  • Burak Tepe

    (Program in Developmental Biology, Baylor College of Medicine)

  • Jeffrey C. Carlson

    (Program in Developmental Biology, Baylor College of Medicine)

  • Kevin Ung

    (Program in Developmental Biology, Baylor College of Medicine)

  • Jennifer Selever

    (Baylor College of Medicine
    Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital)

  • Qingchun Tong

    (Institute of Molecular Medicine, University of Texas Health Science Center)

  • Benjamin R. Arenkiel

    (Program in Developmental Biology, Baylor College of Medicine
    Baylor College of Medicine
    Baylor College of Medicine
    Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital)

Abstract

A mouse study reveals that acetylcholine signalling networks have a role in the regulation of body weight homeostasis, with increased activity of cholinergic neurons decreasing food consumption through downstream hypothalamic targets.

Suggested Citation

  • Alexander M. Herman & Joshua Ortiz-Guzman & Mikhail Kochukov & Isabella Herman & Kathleen B. Quast & Jay M. Patel & Burak Tepe & Jeffrey C. Carlson & Kevin Ung & Jennifer Selever & Qingchun Tong & Ben, 2016. "A cholinergic basal forebrain feeding circuit modulates appetite suppression," Nature, Nature, vol. 538(7624), pages 253-256, October.
  • Handle: RePEc:nat:nature:v:538:y:2016:i:7624:d:10.1038_nature19789
    DOI: 10.1038/nature19789
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature19789
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature19789?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Laia Guardia-Escote & Jordi Blanco & Pia Basaure & Judit Biosca-Brull & Rikst Nynke Verkaik-Schakel & Maria Cabré & Fiona Peris-Sampedro & Cristian Pérez-Fernández & Fernando Sánchez-Santed & Torsten , 2020. "Sex and Exposure to Postnatal Chlorpyrifos Influence the Epigenetics of Feeding-Related Genes in a Transgenic APOE Mouse Model: Long-Term Implications on Body Weight after a High-Fat Diet," IJERPH, MDPI, vol. 18(1), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:538:y:2016:i:7624:d:10.1038_nature19789. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.