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The temporal scaling of Caenorhabditis elegans ageing

Author

Listed:
  • Nicholas Stroustrup

    (Harvard Medical School)

  • Winston E. Anthony

    (Harvard Medical School)

  • Zachary M. Nash

    (Harvard Medical School
    † Present addresses: Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599, USA (Z.M.N.); Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA (A.G.); Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA (I.F.L.-M.); Department of Biology, Northeastern University, Boston, Massachusetts 02115, USA (J.A.).)

  • Vivek Gowda

    (Harvard Medical School)

  • Adam Gomez

    (Harvard Medical School
    † Present addresses: Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599, USA (Z.M.N.); Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA (A.G.); Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA (I.F.L.-M.); Department of Biology, Northeastern University, Boston, Massachusetts 02115, USA (J.A.).)

  • Isaac F. López-Moyado

    (Harvard Medical School
    † Present addresses: Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599, USA (Z.M.N.); Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA (A.G.); Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA (I.F.L.-M.); Department of Biology, Northeastern University, Boston, Massachusetts 02115, USA (J.A.).)

  • Javier Apfeld

    (Harvard Medical School
    † Present addresses: Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, North Carolina 27599, USA (Z.M.N.); Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA (A.G.); Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA (I.F.L.-M.); Department of Biology, Northeastern University, Boston, Massachusetts 02115, USA (J.A.).)

  • Walter Fontana

    (Harvard Medical School)

Abstract

A diverse range of molecular and genetic manipulations all alter lifespan distributions of Caenorhabditis elegans by an apparent stretching or shrinking of time.

Suggested Citation

  • Nicholas Stroustrup & Winston E. Anthony & Zachary M. Nash & Vivek Gowda & Adam Gomez & Isaac F. López-Moyado & Javier Apfeld & Walter Fontana, 2016. "The temporal scaling of Caenorhabditis elegans ageing," Nature, Nature, vol. 530(7588), pages 103-107, February.
    • Handle: RePEc:nat:nature:v:530:y:2016:i:7588:d:10.1038_nature16550
    DOI: 10.1038/nature16550
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    Cited by:

    1. Kan Xie & Helmut Fuchs & Enzo Scifo & Dan Liu & Ahmad Aziz & Juan Antonio Aguilar-Pimentel & Oana Veronica Amarie & Lore Becker & Patricia da Silva-Buttkus & Julia Calzada-Wack & Yi-Li Cho & Yushuang , 2022. "Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice," Nature Communications, Nature, vol. 13(1), pages 1-29, December.
    2. Yifan Yang & Omer Karin & Avi Mayo & Xiaohu Song & Peipei Chen & Ana L. Santos & Ariel B. Lindner & Uri Alon, 2023. "Damage dynamics and the role of chance in the timing of E. coli cell death," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    3. Céline N Martineau & André E X Brown & Patrick Laurent, 2020. "Multidimensional phenotyping predicts lifespan and quantifies health in Caenorhabditis elegans," PLOS Computational Biology, Public Library of Science, vol. 16(7), pages 1-14, July.

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