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Building the foundation for genomics in precision medicine

Author

Listed:
  • Samuel J. Aronson

    (Partners HealthCare Personalized Medicine
    Partners HealthCare Research Information Services and Computing)

  • Heidi L. Rehm

    (Partners HealthCare Personalized Medicine
    Brigham & Women's Hospital
    Harvard Medical School
    The Broad Institute of MIT and Harvard)

Abstract

Precision medicine has the potential to profoundly improve the practice of medicine. However, the advances required will take time to implement. Genetics is already being used to direct clinical decision-making and its contribution is likely to increase. To accelerate these advances, fundamental changes are needed in the infrastructure and mechanisms for data collection, storage and sharing. This will create a continuously learning health-care system with seamless cycling between clinical care and research. Patients must be educated about the benefits of sharing data. The building blocks for such a system are already forming and they will accelerate the adoption of precision medicine.

Suggested Citation

  • Samuel J. Aronson & Heidi L. Rehm, 2015. "Building the foundation for genomics in precision medicine," Nature, Nature, vol. 526(7573), pages 336-342, October.
    • Handle: RePEc:nat:nature:v:526:y:2015:i:7573:d:10.1038_nature15816
    DOI: 10.1038/nature15816
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    Cited by:

    1. Amalia R. Miller & Catherine Tucker, 2018. "Privacy Protection, Personalized Medicine, and Genetic Testing," Management Science, INFORMS, vol. 64(10), pages 4648-4668, October.
    2. Huchang Liao & Ming Tang & Li Luo & Chunyang Li & Francisco Chiclana & Xiao-Jun Zeng, 2018. "A Bibliometric Analysis and Visualization of Medical Big Data Research," Sustainability, MDPI, vol. 10(1), pages 1-18, January.
    3. Forrest Briscoe & Ifeoma Ajunwa & Allison Gaddis & Jennifer McCormick, 2020. "Evolving public views on the value of one’s DNA and expectations for genomic database governance: Results from a national survey," PLOS ONE, Public Library of Science, vol. 15(3), pages 1-10, March.
    4. Rohini Chakravarthy & Sarah C Stallings & Michael Williams & Megan Hollister & Mario Davidson & Juan Canedo & Consuelo H Wilkins, 2020. "Factors influencing precision medicine knowledge and attitudes," PLOS ONE, Public Library of Science, vol. 15(11), pages 1-14, November.

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