IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v526y2015i7573d10.1038_nature15693.html
   My bibliography  Save this article

Encoding of action by the Purkinje cells of the cerebellum

Author

Listed:
  • David J. Herzfeld

    (Laboratory for Computational Motor Control, Johns Hopkins University School of Medicine)

  • Yoshiko Kojima

    (Washington National Primate Center, University of Washington)

  • Robijanto Soetedjo

    (Washington National Primate Center, University of Washington)

  • Reza Shadmehr

    (Laboratory for Computational Motor Control, Johns Hopkins University School of Medicine)

Abstract

Recording from Purkinje cells in monkeys, this study found that the combined simple-spike responses of bursting and pausing Purkinje cells, but not either population alone, predicted the real-time speed of saccades; moreover, when Purkinje cells were organized according to their complex-spike field, the population responses encoded both speed and direction of the eye during saccades via a gain field.

Suggested Citation

  • David J. Herzfeld & Yoshiko Kojima & Robijanto Soetedjo & Reza Shadmehr, 2015. "Encoding of action by the Purkinje cells of the cerebellum," Nature, Nature, vol. 526(7573), pages 439-442, October.
    • Handle: RePEc:nat:nature:v:526:y:2015:i:7573:d:10.1038_nature15693
    DOI: 10.1038/nature15693
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature15693
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature15693?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Omid A. Zobeiri & Kathleen E. Cullen, 2024. "Cerebellar Purkinje cells combine sensory and motor information to predict the sensory consequences of active self-motion in macaques," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    2. François G. C. Blot & Joshua J. White & Amy van Hattem & Licia Scotti & Vaishnavi Balaji & Youri Adolfs & R. Jeroen Pasterkamp & Chris I. De Zeeuw & Martijn Schonewille, 2023. "Purkinje cell microzones mediate distinct kinematics of a single movement," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    3. Simon P Orozco & Scott T Albert & Reza Shadmehr, 2021. "Adaptive control of movement deceleration during saccades," PLOS Computational Biology, Public Library of Science, vol. 17(7), pages 1-30, July.
    4. Naveen Sendhilnathan & Andreea C. Bostan & Peter L. Strick & Michael E. Goldberg, 2024. "A cerebro-cerebellar network for learning visuomotor associations," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    5. Akshay Markanday & Sungho Hong & Junya Inoue & Erik Schutter & Peter Thier, 2023. "Multidimensional cerebellar computations for flexible kinematic control of movements," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    6. Chris. I. De Zeeuw & Julius Koppen & George. G. Bregman & Marit Runge & Devika Narain, 2023. "Heterogeneous encoding of temporal stimuli in the cerebellar cortex," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    7. Li, Tianyu & Wu, Yong & Yang, Lijian & Fu, Ziying & Jia, Ya, 2023. "Neuronal morphology and network properties modulate signal propagation in multi-layer feedforward network," Chaos, Solitons & Fractals, Elsevier, vol. 172(C).
    8. Julian Rossbroich & Daniel Trotter & John Beninger & Katalin Tóth & Richard Naud, 2021. "Linear-nonlinear cascades capture synaptic dynamics," PLOS Computational Biology, Public Library of Science, vol. 17(3), pages 1-27, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:526:y:2015:i:7573:d:10.1038_nature15693. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.