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A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion

Author

Listed:
  • Niv Scott

    (Weizmann Institute of Science)

  • Matthias Prigge

    (Weizmann Institute of Science)

  • Ofer Yizhar

    (Weizmann Institute of Science)

  • Tali Kimchi

    (Weizmann Institute of Science)

Abstract

Sexual dimorphism in neuronal circuits is proposed to underlie sex differences in behaviour, such as virgin female mice acting maternally toward alien pups, while males ignore or attack them; here the authors show that specific tyrosine hydroxylase-expressing neurons in the hypothalamus are more numerous in mothers than in virgin females and males, and that they control parental behaviour in a sex-specific manner.

Suggested Citation

  • Niv Scott & Matthias Prigge & Ofer Yizhar & Tali Kimchi, 2015. "A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion," Nature, Nature, vol. 525(7570), pages 519-522, September.
    • Handle: RePEc:nat:nature:v:525:y:2015:i:7570:d:10.1038_nature15378
    DOI: 10.1038/nature15378
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    Cited by:

    1. Solomiia Korchynska & Patrick Rebernik & Marko Pende & Laura Boi & Alán Alpár & Ramon Tasan & Klaus Becker & Kira Balueva & Saiedeh Saghafi & Peer Wulff & Tamas L. Horvath & Gilberto Fisone & Hans-Ulr, 2022. "A hypothalamic dopamine locus for psychostimulant-induced hyperlocomotion in mice," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Susan E. Erdman, 2021. "Microbial Muses: Threads of Our Inner Wisdom," Challenges, MDPI, vol. 12(1), pages 1-4, March.

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