IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v523y2015i7562d10.1038_nature14614.html
   My bibliography  Save this article

Mitochondrial reticulum for cellular energy distribution in muscle

Author

Listed:
  • Brian Glancy

    (National Heart Lung and Blood Institute, National Institutes of Health)

  • Lisa M. Hartnell

    (National Cancer Institute, National Institutes of Health)

  • Daniela Malide

    (National Heart Lung and Blood Institute, National Institutes of Health)

  • Zu-Xi Yu

    (National Heart Lung and Blood Institute, National Institutes of Health)

  • Christian A. Combs

    (National Heart Lung and Blood Institute, National Institutes of Health)

  • Patricia S. Connelly

    (National Heart Lung and Blood Institute, National Institutes of Health)

  • Sriram Subramaniam

    (National Cancer Institute, National Institutes of Health)

  • Robert S. Balaban

    (National Heart Lung and Blood Institute, National Institutes of Health)

Abstract

Mitochondria are shown to form a conductive pathway throughout the cell in the form of a proton motive force, and throughout this network, mitochondrial protein localization seems to be varied, allowing optimized generation and utilization of the mitochondrial membrane potential; the rapid energy distribution network, which depends on conduction rather than diffusion, could explain how the muscle can rapidly respond to energy demands.

Suggested Citation

  • Brian Glancy & Lisa M. Hartnell & Daniela Malide & Zu-Xi Yu & Christian A. Combs & Patricia S. Connelly & Sriram Subramaniam & Robert S. Balaban, 2015. "Mitochondrial reticulum for cellular energy distribution in muscle," Nature, Nature, vol. 523(7562), pages 617-620, July.
  • Handle: RePEc:nat:nature:v:523:y:2015:i:7562:d:10.1038_nature14614
    DOI: 10.1038/nature14614
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature14614
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature14614?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Prasanna Katti & Alexander S. Hall & Hailey A. Parry & Peter T. Ajayi & Yuho Kim & T. Bradley Willingham & Christopher K. E. Bleck & Han Wen & Brian Glancy, 2022. "Mitochondrial network configuration influences sarcomere and myosin filament structure in striated muscles," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
    2. Lance T. Denes & Chase P. Kelley & Eric T. Wang, 2021. "Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle," Nature Communications, Nature, vol. 12(1), pages 1-19, December.
    3. Prasanna Katti & Peter T. Ajayi & Angel Aponte & Christopher K. E. Bleck & Brian Glancy, 2022. "Identification of evolutionarily conserved regulators of muscle mitochondrial network organization," Nature Communications, Nature, vol. 13(1), pages 1-18, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:523:y:2015:i:7562:d:10.1038_nature14614. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.