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Caenorhabditis elegans pathways that surveil and defend mitochondria

Author

Listed:
  • Ying Liu

    (Massachusetts General Hospital
    Harvard Medical School
    Present address: State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.)

  • Buck S. Samuel

    (Massachusetts General Hospital
    Harvard Medical School)

  • Peter C. Breen

    (Massachusetts General Hospital
    Harvard Medical School)

  • Gary Ruvkun

    (Massachusetts General Hospital
    Harvard Medical School)

Abstract

A genome-wide RNA interference screen in Caenorhabditis elegans identifies 45 genes with roles in protective pathways following drug- and genetic-disruption-induced mitochondrial inhibition.

Suggested Citation

  • Ying Liu & Buck S. Samuel & Peter C. Breen & Gary Ruvkun, 2014. "Caenorhabditis elegans pathways that surveil and defend mitochondria," Nature, Nature, vol. 508(7496), pages 406-410, April.
    • Handle: RePEc:nat:nature:v:508:y:2014:i:7496:d:10.1038_nature13204
    DOI: 10.1038/nature13204
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    Cited by:

    1. Eunah Kim & Andrea Annibal & Yujin Lee & Hae-Eun H. Park & Seokjin Ham & Dae-Eun Jeong & Younghun Kim & Sangsoon Park & Sujeong Kwon & Yoonji Jung & JiSoo Park & Sieun S. Kim & Adam Antebi & Seung-Jae, 2023. "Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Silvia Maglioni & Alfonso Schiavi & Marlen Melcher & Vanessa Brinkmann & Zhongrui Luo & Anna Laromaine & Nuno Raimundo & Joel N. Meyer & Felix Distelmaier & Natascia Ventura, 2022. "Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans," Nature Communications, Nature, vol. 13(1), pages 1-21, December.

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