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A committed precursor to innate lymphoid cells

Author

Listed:
  • Michael G. Constantinides

    (Committee on Immunology, The Howard Hughes Medical Institute, University of Chicago)

  • Benjamin D. McDonald

    (Committee on Immunology, The Howard Hughes Medical Institute, University of Chicago)

  • Philip A. Verhoef

    (Committee on Immunology, The Howard Hughes Medical Institute, University of Chicago)

  • Albert Bendelac

    (Committee on Immunology, The Howard Hughes Medical Institute, University of Chicago)

Abstract

A committed precursor to innate lymphoid cell lineages, but not classical natural killer and lymphoid tissue inducer cells, is derived from common lymphoid precursors and distinguished by high levels of expression of the transcription factor PLZF.

Suggested Citation

  • Michael G. Constantinides & Benjamin D. McDonald & Philip A. Verhoef & Albert Bendelac, 2014. "A committed precursor to innate lymphoid cells," Nature, Nature, vol. 508(7496), pages 397-401, April.
    • Handle: RePEc:nat:nature:v:508:y:2014:i:7496:d:10.1038_nature13047
    DOI: 10.1038/nature13047
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    Cited by:

    1. Xusheng Zhang & Xintong Gao & Zhen Liu & Fei Shao & Dou Yu & Min Zhao & Xiwen Qin & Shuo Wang, 2024. "Microbiota regulates the TET1-mediated DNA hydroxymethylation program in innate lymphoid cell differentiation," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    2. Nian Liu & Jiacheng He & Dongdong Fan & Yang Gu & Jianyi Wang & Huimu Li & Xiaoxiao Zhu & Ying Du & Yong Tian & Benyu Liu & Zusen Fan, 2022. "Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    3. Paula A. Clark & Mayuri Gogoi & Noe Rodriguez-Rodriguez & Ana C. F. Ferreira & Jane E. Murphy & Jennifer A. Walker & Alastair Crisp & Helen E. Jolin & Jacqueline D. Shields & Andrew N. J. McKenzie, 2024. "Recipient tissue microenvironment determines developmental path of intestinal innate lymphoid progenitors," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    4. Panpan Tian & Wenwen Yang & Xiaowei Guo & Tixiao Wang & Siyu Tan & Renhui Sun & Rong Xiao & Yuzhen Wang & Deyan Jiao & Yachen Xu & Yanfei Wei & Zhuanchang Wu & Chunyang Li & Lifen Gao & Chunhong Ma & , 2023. "Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    5. Hiroki Furuya & Yosuke Toda & Arifumi Iwata & Mizuki Kanai & Kodai Kato & Takashi Kumagai & Takahiro Kageyama & Shigeru Tanaka & Lisa Fujimura & Akemi Sakamoto & Masahiko Hatano & Akira Suto & Kotaro , 2024. "Stage-specific GATA3 induction promotes ILC2 development after lineage commitment," Nature Communications, Nature, vol. 15(1), pages 1-16, December.

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