IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v508y2014i7494d10.1038_nature13012.html
   My bibliography  Save this article

Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans

Author

Listed:
  • En-Zhi Shen

    (College of Biological Sciences, China Agricultural University, Beijing 100094, China
    National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Chun-Qing Song

    (College of Biological Sciences, China Agricultural University, Beijing 100094, China
    National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Yuan Lin

    (State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China)

  • Wen-Hong Zhang

    (National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Pei-Fang Su

    (National Cheng Kung University, Tainan 70101, Taiwan)

  • Wen-Yuan Liu

    (National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Pan Zhang

    (National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Jiejia Xu

    (State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China)

  • Na Lin

    (State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China)

  • Cheng Zhan

    (National Institute of Biological Sciences, Beijing, Beijing 102206, China)

  • Xianhua Wang

    (State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China)

  • Yu Shyr

    (Vanderbilt Centre for Quantitative Sciences, Vanderbilt University)

  • Heping Cheng

    (State Key Laboratory of Biomembrane and Membrane Biotechnology, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China)

  • Meng-Qiu Dong

    (National Institute of Biological Sciences, Beijing, Beijing 102206, China)

Abstract

In Caenorhabditis elegans, mitochondrial activity as measured by the frequency of the mitochondrial flash in young adult animals is a powerful predictor of lifespan across genetic, environmental and stochastic factors.

Suggested Citation

  • En-Zhi Shen & Chun-Qing Song & Yuan Lin & Wen-Hong Zhang & Pei-Fang Su & Wen-Yuan Liu & Pan Zhang & Jiejia Xu & Na Lin & Cheng Zhan & Xianhua Wang & Yu Shyr & Heping Cheng & Meng-Qiu Dong, 2014. "Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans," Nature, Nature, vol. 508(7494), pages 128-132, April.
    • Handle: RePEc:nat:nature:v:508:y:2014:i:7494:d:10.1038_nature13012
    DOI: 10.1038/nature13012
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature13012
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature13012?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Weilin Kong & Guoli Gu & Tong Dai & Beibei Chen & Yanli Wang & Zheng Zeng & Mintie Pu, 2024. "ELO-6 expression predicts longevity in isogenic populations of Caenorhabditis elegans," Nature Communications, Nature, vol. 15(1), pages 1-16, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:508:y:2014:i:7494:d:10.1038_nature13012. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.