IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v499y2013i7457d10.1038_nature12212.html
   My bibliography  Save this article

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

Author

Listed:
  • Sheetal R. Modi

    (Howard Hughes Medical Institute, and Center for BioDynamics, Boston University)

  • Henry H. Lee

    (Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
    Present address: Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.)

  • Catherine S. Spina

    (Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
    Boston University School of Medicine, 715 Albany Street
    Wyss Institute for Biologically Inspired Engineering, Harvard University)

  • James J. Collins

    (Howard Hughes Medical Institute, and Center for BioDynamics, Boston University
    Boston University School of Medicine, 715 Albany Street
    Wyss Institute for Biologically Inspired Engineering, Harvard University)

Abstract

By exploring the phageome in mice, antibiotic treatment is shown to lead to enrichment of phage-encoded genes that are related to antibiotic resistance.

Suggested Citation

  • Sheetal R. Modi & Henry H. Lee & Catherine S. Spina & James J. Collins, 2013. "Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome," Nature, Nature, vol. 499(7457), pages 219-222, July.
    • Handle: RePEc:nat:nature:v:499:y:2013:i:7457:d:10.1038_nature12212
    DOI: 10.1038/nature12212
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature12212
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature12212?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Rohan Maddamsetti & Yi Yao & Teng Wang & Junheng Gao & Vincent T. Huang & Grayson S. Hamrick & Hye-In Son & Lingchong You, 2024. "Duplicated antibiotic resistance genes reveal ongoing selection and horizontal gene transfer in bacteria," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    2. Patrick Munk & Christian Brinch & Frederik Duus Møller & Thomas N. Petersen & Rene S. Hendriksen & Anne Mette Seyfarth & Jette S. Kjeldgaard & Christina Aaby Svendsen & Bram Bunnik & Fanny Berglund & , 2022. "Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    3. Suzanne Humphrey & Álvaro San Millán & Macarena Toll-Riera & John Connolly & Alejandra Flor-Duro & John Chen & Carles Ubeda & R. Craig MacLean & José R. Penadés, 2021. "Staphylococcal phages and pathogenicity islands drive plasmid evolution," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
    4. Friederike S Rossmann & Tomas Racek & Dominique Wobser & Jacek Puchalka & Elaine M Rabener & Matthias Reiger & Antoni P A Hendrickx & Ann-Kristin Diederich & Kirsten Jung & Christoph Klein & Johannes , 2015. "Phage-mediated Dispersal of Biofilm and Distribution of Bacterial Virulence Genes Is Induced by Quorum Sensing," PLOS Pathogens, Public Library of Science, vol. 11(2), pages 1-17, February.
    5. Milva Pepi & Silvano Focardi, 2021. "Antibiotic-Resistant Bacteria in Aquaculture and Climate Change: A Challenge for Health in the Mediterranean Area," IJERPH, MDPI, vol. 18(11), pages 1-31, May.
    6. Shao-Ming Gao & Han-Lan Fei & Qi Li & Li-Ying Lan & Li-Nan Huang & Peng-Fei Fan, 2024. "Eco-evolutionary dynamics of gut phageome in wild gibbons (Hoolock tianxing) with seasonal diet variations," Nature Communications, Nature, vol. 15(1), pages 1-13, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:499:y:2013:i:7457:d:10.1038_nature12212. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.