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A call for transparent reporting to optimize the predictive value of preclinical research

Author

Listed:
  • Story C. Landis

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Susan G. Amara

    (University of Pittsburgh School of Medicine)

  • Khusru Asadullah

    (Bayer HealthCare)

  • Chris P. Austin

    (National Center for Advancing Translational Sciences, NIH)

  • Robi Blumenstein

    (CHDI Management/CHDI Foundation)

  • Eileen W. Bradley

    (Center for Review, NIH, Bethesda, Maryland 20892, USA)

  • Ronald G. Crystal

    (Weill Cornell Medical College)

  • Robert B. Darnell

    (Howard Hughes Medical Institute, The Rockefeller University)

  • Robert J. Ferrante

    (University of Pittsburgh)

  • Howard Fillit

    (Alzheimer's Drug Discovery Foundation)

  • Robert Finkelstein

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Marc Fisher

    (University of Massachusetts Medical School)

  • Howard E. Gendelman

    (University of Nebraska Medical Center)

  • Robert M. Golub

    (JAMA)

  • John L. Goudreau

    (Michigan State University)

  • Robert A. Gross

    (University of Rochester Medical Center)

  • Amelie K. Gubitz

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Sharon E. Hesterlee

    (Parent Project Muscular Dystrophy)

  • David W. Howells

    (The Florey Institute of Neuroscience and Mental Health, University of Melbourne)

  • John Huguenard

    (Neurology and Neurological Sciences and Cellular and Molecular Physiology, Stanford University)

  • Katrina Kelner

    (Science Translational Medicine, AAAS, Washington DC 22201, USA)

  • Walter Koroshetz

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Dimitri Krainc

    (Harvard Medical School, Massachusetts General Hospital)

  • Stanley E. Lazic

    (F. Hoffmann-La Roche)

  • Michael S. Levine

    (University of California Los Angeles)

  • Malcolm R. Macleod

    (University of Edinburgh, Western General Hospital)

  • John M. McCall

    (PharMac LLC)

  • Richard T. Moxley III

    (University of Rochester Medical Center, School of Medicine and Dentistry)

  • Kalyani Narasimhan

    (Nature Neuroscience)

  • Linda J. Noble

    (University of California San Francisco)

  • Steve Perrin

    (ALS Therapy Development Institute)

  • John D. Porter

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Oswald Steward

    (Reeve-Irvine Research Center, University of California Irvine)

  • Ellis Unger

    (Office of New Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland 20993, USA)

  • Ursula Utz

    (National Institute of Neurological Disorders and Stroke, NIH)

  • Shai D. Silberberg

    (National Institute of Neurological Disorders and Stroke, NIH)

Abstract

Deficiencies in methods reporting in animal experimentation lead to difficulties in reproducing experiments; the authors propose a set of reporting standards to improve scientific communication and study design.

Suggested Citation

  • Story C. Landis & Susan G. Amara & Khusru Asadullah & Chris P. Austin & Robi Blumenstein & Eileen W. Bradley & Ronald G. Crystal & Robert B. Darnell & Robert J. Ferrante & Howard Fillit & Robert Finke, 2012. "A call for transparent reporting to optimize the predictive value of preclinical research," Nature, Nature, vol. 490(7419), pages 187-191, October.
    • Handle: RePEc:nat:nature:v:490:y:2012:i:7419:d:10.1038_nature11556
    DOI: 10.1038/nature11556
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    Cited by:

    1. Olivia Hogue & Tucker Harvey & Dena Crozier & Claire Sonneborn & Abagail Postle & Hunter Block-Beach & Eashwar Somasundaram & Francis J May & Monica Snyder Braun & Felicia L Pasadyn & Khandi King & Ca, 2022. "Statistical practice and transparent reporting in the neurosciences: Preclinical motor behavioral experiments," PLOS ONE, Public Library of Science, vol. 17(3), pages 1-17, March.
    2. Zacharias Maniadis & Fabio Tufano & John A. List, 2017. "To Replicate or Not To Replicate? Exploring Reproducibility in Economics through the Lens of a Model and a Pilot Study," Economic Journal, Royal Economic Society, vol. 127(605), pages 209-235, October.

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