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Structural and genetic basis for development of broadly neutralizing influenza antibodies

Author

Listed:
  • Daniel Lingwood

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Patrick M. McTamney

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Hadi M. Yassine

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • James R. R. Whittle

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Xiaoti Guo

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Jeffrey C. Boyington

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Chih-Jen Wei

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

  • Gary J. Nabel

    (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health)

Abstract

The events leading to the generation of broadly neutralizing antibodies to influenza viruses, which may hold the key to developing a universal flu vaccine, are elucidated.

Suggested Citation

  • Daniel Lingwood & Patrick M. McTamney & Hadi M. Yassine & James R. R. Whittle & Xiaoti Guo & Jeffrey C. Boyington & Chih-Jen Wei & Gary J. Nabel, 2012. "Structural and genetic basis for development of broadly neutralizing influenza antibodies," Nature, Nature, vol. 489(7417), pages 566-570, September.
    • Handle: RePEc:nat:nature:v:489:y:2012:i:7417:d:10.1038_nature11371
    DOI: 10.1038/nature11371
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    Cited by:

    1. Eike-Christian Wamhoff & Larance Ronsard & Jared Feldman & Grant A. Knappe & Blake M. Hauser & Anna Romanov & James Brett Case & Shilpa Sanapala & Evan C. Lam & Kerri J. St. Denis & Julie Boucau & Amy, 2024. "Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    2. Larance Ronsard & Ashraf S. Yousif & Faez Amokrane Nait Mohamed & Jared Feldman & Vintus Okonkwo & Caitlin McCarthy & Julia Schnabel & Timothy Caradonna & Ralston M. Barnes & Daniel Rohrer & Nils Lonb, 2023. "Engaging an HIV vaccine target through the acquisition of low B cell affinity," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    3. Brian M. Petersen & Monica B. Kirby & Karson M. Chrispens & Olivia M. Irvin & Isabell K. Strawn & Cyrus M. Haas & Alexis M. Walker & Zachary T. Baumer & Sophia A. Ulmer & Edgardo Ayala & Emily R. Rhod, 2024. "An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

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