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Protocadherins mediate dendritic self-avoidance in the mammalian nervous system

Author

Listed:
  • Julie L. Lefebvre

    (Harvard University, 52 Oxford Street, Cambridge, Massachusetts 02138, USA)

  • Dimitar Kostadinov

    (Harvard University, 52 Oxford Street, Cambridge, Massachusetts 02138, USA)

  • Weisheng V. Chen

    (Columbia University Medical Center, 701 West 168th Street, New York, New York 10032, USA)

  • Tom Maniatis

    (Columbia University Medical Center, 701 West 168th Street, New York, New York 10032, USA)

  • Joshua R. Sanes

    (Harvard University, 52 Oxford Street, Cambridge, Massachusetts 02138, USA)

Abstract

Protocadherins are found to potentially provide the molecular diversity and complexity required to promote dendritic self-avoidance in mouse retina and cerebellum.

Suggested Citation

  • Julie L. Lefebvre & Dimitar Kostadinov & Weisheng V. Chen & Tom Maniatis & Joshua R. Sanes, 2012. "Protocadherins mediate dendritic self-avoidance in the mammalian nervous system," Nature, Nature, vol. 488(7412), pages 517-521, August.
    • Handle: RePEc:nat:nature:v:488:y:2012:i:7412:d:10.1038_nature11305
    DOI: 10.1038/nature11305
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    Cited by:

    1. Mehmet Can Uçar & Dmitrii Kamenev & Kazunori Sunadome & Dominik Fachet & Francois Lallemend & Igor Adameyko & Saida Hadjab & Edouard Hannezo, 2021. "Theory of branching morphogenesis by local interactions and global guidance," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
    2. Yueqi Wang & Simone Chiola & Guang Yang & Chad Russell & Celeste J. Armstrong & Yuanyuan Wu & Jay Spampanato & Paisley Tarboton & H. M. Arif Ullah & Nicolas U. Edgar & Amelia N. Chang & David A. Harmi, 2022. "Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes," Nature Communications, Nature, vol. 13(1), pages 1-25, December.
    3. Jie Zhong & Chaodong Wang & Dan Zhang & Xiaoli Yao & Quanzhen Zhao & Xusheng Huang & Feng Lin & Chun Xue & Yaqing Wang & Ruojie He & Xu-Ying Li & Qibin Li & Mingbang Wang & Shaoli Zhao & Shabbir Khan , 2024. "PCDHA9 as a candidate gene for amyotrophic lateral sclerosis," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
    4. Jie Cheng & Yamei Yu & Xingyu Wang & Xi Zheng & Ting Liu & Daojun Hu & Yongfeng Jin & Ying Lai & Tian-Min Fu & Qiang Chen, 2023. "Structural basis for the self-recognition of sDSCAM in Chelicerata," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
    5. Xiao Ge & Haiyan Huang & Keqi Han & Wangjie Xu & Zhaoxia Wang & Qiang Wu, 2023. "Outward-oriented sites within clustered CTCF boundaries are key for intra-TAD chromatin interactions and gene regulation," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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