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Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

Author

Listed:
  • Junke Zheng

    (University of Texas Southwestern Medical Center
    Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine)

  • Masato Umikawa

    (University of Texas Southwestern Medical Center
    University of the Ryukyus, Okinawa 903-0215, Japan)

  • Changhao Cui

    (University of Texas Southwestern Medical Center)

  • Jiyuan Li

    (University of Texas Southwestern Medical Center)

  • Xiaoli Chen

    (University of Texas Southwestern Medical Center)

  • Chaozheng Zhang

    (University of Texas Southwestern Medical Center)

  • HoangDinh Huynh

    (University of Texas Southwestern Medical Center)

  • Xunlei Kang

    (University of Texas Southwestern Medical Center)

  • Robert Silvany

    (University of Texas Southwestern Medical Center)

  • Xuan Wan

    (University of Texas Southwestern Medical Center)

  • Jingxiao Ye

    (University of Texas Southwestern Medical Center)

  • Alberto Puig Cantó

    (University of Texas Southwestern Medical Center)

  • Shu-Hsia Chen

    (Mount Sinai School of Medicine)

  • Huan-You Wang

    (University of California San Diego)

  • E. Sally Ward

    (University of Texas Southwestern Medical Center)

  • Cheng Cheng Zhang

    (University of Texas Southwestern Medical Center)

Abstract

The binding of angiopoietin-like proteins to immune-inhibitory receptors maintains ‘stemness’ of haematopoietic stem cells and supports leukaemia development.

Suggested Citation

  • Junke Zheng & Masato Umikawa & Changhao Cui & Jiyuan Li & Xiaoli Chen & Chaozheng Zhang & HoangDinh Huynh & Xunlei Kang & Robert Silvany & Xuan Wan & Jingxiao Ye & Alberto Puig Cantó & Shu-Hsia Chen &, 2012. "Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development," Nature, Nature, vol. 485(7400), pages 656-660, May.
    • Handle: RePEc:nat:nature:v:485:y:2012:i:7400:d:10.1038_nature11095
    DOI: 10.1038/nature11095
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    Cited by:

    1. Pengcheng Shang & Joshua D. Simpson & Gwen M. Taylor & Danica M. Sutherland & Olivia L. Welsh & Pavithra Aravamudhan & Rita Dos Santos Natividade & Kristina Schwab & Joshua J. Michel & Amanda C. Pohol, 2023. "Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Dan-Pei Li & Li Huang & Ran-Ran Kan & Xiao-Yu Meng & Shu-Yun Wang & Hua-Jie Zou & Ya-Ming Guo & Pei-Qiong Luo & Li-Meng Pan & Yu-Xi Xiang & Bei-Bei Mao & Yu-Yu Xie & Zhi-Han Wang & Min Yang & Rui He &, 2023. "LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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