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Control of ground-state pluripotency by allelic regulation of Nanog

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  • Yusuke Miyanari

    (Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM U964, Université de Strasbourg, F-67404 Illkirch, Cité Universitaire de Strasbourg)

  • Maria-Elena Torres-Padilla

    (Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM U964, Université de Strasbourg, F-67404 Illkirch, Cité Universitaire de Strasbourg)

Abstract

Tight regulation of Nanog dose at the chromosome level is important for the acquisition of pluripotency during development.

Suggested Citation

  • Yusuke Miyanari & Maria-Elena Torres-Padilla, 2012. "Control of ground-state pluripotency by allelic regulation of Nanog," Nature, Nature, vol. 483(7390), pages 470-473, March.
    • Handle: RePEc:nat:nature:v:483:y:2012:i:7390:d:10.1038_nature10807
    DOI: 10.1038/nature10807
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    Cited by:

    1. Gemma Noviello & Rutger A. F. Gjaltema & Edda G. Schulz, 2023. "CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
    2. Sabine C Fischer & Elena Corujo-Simon & Joaquin Lilao-Garzon & Ernst H K Stelzer & Silvia Muñoz-Descalzo, 2020. "The transition from local to global patterns governs the differentiation of mouse blastocysts," PLOS ONE, Public Library of Science, vol. 15(5), pages 1-29, May.
    3. Nicolas Allègre & Sabine Chauveau & Cynthia Dennis & Yoan Renaud & Dimitri Meistermann & Lorena Valverde Estrella & Pierre Pouchin & Michel Cohen-Tannoudji & Laurent David & Claire Chazaud, 2022. "NANOG initiates epiblast fate through the coordination of pluripotency genes expression," Nature Communications, Nature, vol. 13(1), pages 1-13, December.

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