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Cyclin D1 multitasks

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  • Jiri Bartek

    (Jiri Bartek and Jiri Lukas are at the Danish Cancer Society, Centre for Genotoxic Stress Research, Copenhagen, Denmark. J.B. is also at the Institute of Molecular and Translational Medicine, Palacky University, Olomouc, Czech Republic.)

  • Jiri Lukas

    (Jiri Bartek and Jiri Lukas are at the Danish Cancer Society, Centre for Genotoxic Stress Research, Copenhagen, Denmark. J.B. is also at the Institute of Molecular and Translational Medicine, Palacky University, Olomouc, Czech Republic.)

Abstract

Cyclin D1 is one of the drivers of the cell cycle, and its deregulation may promote the development of tumours. Surprisingly, this protein also mediates the repair of damaged DNA, a mechanism that commonly prevents cancer. See Letter p.230

Suggested Citation

  • Jiri Bartek & Jiri Lukas, 2011. "Cyclin D1 multitasks," Nature, Nature, vol. 474(7350), pages 171-172, June.
  • Handle: RePEc:nat:nature:v:474:y:2011:i:7350:d:10.1038_474171a
    DOI: 10.1038/474171a
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    Cited by:

    1. Noreddine Benkerroum, 2020. "Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action," IJERPH, MDPI, vol. 17(2), pages 1-28, January.

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