IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v472y2011i7343d10.1038_nature09905.html
   My bibliography  Save this article

Metabolic trade-offs and the maintenance of the fittest and the flattest

Author

Listed:
  • Robert E. Beardmore

    (Imperial College London, Huxley Building, 180 Queen’s Gate, London SW7 2A7, UK
    Present address: Biosciences, Geoffrey Pope Building, Streatham Campus, University of Exeter, Exeter, Devon, EX4 4SB, UK.)

  • Ivana Gudelj

    (Imperial College London, Huxley Building, 180 Queen’s Gate, London SW7 2A7, UK
    Present address: Biosciences, Geoffrey Pope Building, Streatham Campus, University of Exeter, Exeter, Devon, EX4 4SB, UK.)

  • David A. Lipson

    (San Diego State University)

  • Laurence D. Hurst

    (University of Bath, Claverton Down, Bath, BA2 7AY, UK)

Abstract

The maintenance of diversity Environmental heterogeneity is considered an important factor in the maintenance of species diversity. Yet diversity is also maintained in some homogeneous environments. Ecological theory has struggled, in particular, to account for the diversity of metabolic strategies found in seemingly homogeneous populations of microbes grown in chemostats. An explanation that fits the experimental data is now offered: at realistic mutation rates there is coexistence between fit genotypes that have unfit neighbours on the adaptive landscape, and less fit but more mutationally robust (sometimes called 'flat') genotypes.

Suggested Citation

  • Robert E. Beardmore & Ivana Gudelj & David A. Lipson & Laurence D. Hurst, 2011. "Metabolic trade-offs and the maintenance of the fittest and the flattest," Nature, Nature, vol. 472(7343), pages 342-346, April.
    • Handle: RePEc:nat:nature:v:472:y:2011:i:7343:d:10.1038_nature09905
    DOI: 10.1038/nature09905
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature09905
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature09905?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. González Casanova, Adrián & Miró Pina, Verónica & Pardo, Juan Carlos, 2020. "The Wright–Fisher model with efficiency," Theoretical Population Biology, Elsevier, vol. 132(C), pages 33-46.
    2. Olga A Nev & Richard J Lindsay & Alys Jepson & Lisa Butt & Robert E Beardmore & Ivana Gudelj, 2021. "Predicting microbial growth dynamics in response to nutrient availability," PLOS Computational Biology, Public Library of Science, vol. 17(3), pages 1-20, March.
    3. Wei Fan & Jingchao Yuan & Jinggui Wu & Hongguang Cai, 2023. "Effects of Straw Maize on the Bacterial Community and Carbon Stability at Different Soil Depths," Agriculture, MDPI, vol. 13(7), pages 1-15, June.
    4. Ivana Gudelj & Margie Kinnersley & Peter Rashkov & Karen Schmidt & Frank Rosenzweig, 2016. "Stability of Cross-Feeding Polymorphisms in Microbial Communities," PLOS Computational Biology, Public Library of Science, vol. 12(12), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:472:y:2011:i:7343:d:10.1038_nature09905. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.