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Lessons on longevity from budding yeast

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  • Matt Kaeberlein

    (University of Washington
    Institute of Aging Research, Guangdong Medical College)

Abstract

The past decade has seen fundamental advances in our understanding of the ageing process and raised optimism that interventions to slow ageing may be on the horizon. Studies of budding yeast have made immense contributions to this progress. Yeast longevity factors have now been shown to modulate ageing in invertebrate and mammalian models, and studies of yeast have resulted in some of the best candidates for anti-ageing drugs currently in development. The first interventions to slow human ageing may spring from the humble yeast.

Suggested Citation

  • Matt Kaeberlein, 2010. "Lessons on longevity from budding yeast," Nature, Nature, vol. 464(7288), pages 513-519, March.
    • Handle: RePEc:nat:nature:v:464:y:2010:i:7288:d:10.1038_nature08981
    DOI: 10.1038/nature08981
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    Cited by:

    1. Arthur Fischbach & Angela Johns & Kara L. Schneider & Xinxin Hao & Peter Tessarz & Thomas Nyström, 2023. "Artificial Hsp104-mediated systems for re-localizing protein aggregates," Nature Communications, Nature, vol. 14(1), pages 1-14, December.

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