IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v450y2007i7166d10.1038_nature06203.html
   My bibliography  Save this article

A translocation signal for delivery of oomycete effector proteins into host plant cells

Author

Listed:
  • Stephen C. Whisson

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Petra C. Boevink

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Lucy Moleleki

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Anna O. Avrova

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Juan G. Morales

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Eleanor M. Gilroy

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Miles R. Armstrong

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Severine Grouffaud

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK
    Aberdeen Oomycete Group, University of Aberdeen, Institute of Medical Sciences)

  • Pieter van West

    (Aberdeen Oomycete Group, University of Aberdeen, Institute of Medical Sciences)

  • Sean Chapman

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Ingo Hein

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Ian K. Toth

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Leighton Pritchard

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

  • Paul R. J. Birch

    (Plant Pathology Programme, Scottish Crop Research Institute, Invergowrie, Dundee DD2 5DA, UK)

Abstract

Common entrance Many plant and animal pathogens evade host immunity systems by injecting virulence or effector proteins into the host cells. A study of the fungus Phytophthora infestans, the potato blight pathogen, has identified a conserved peptide motif in effector proteins that is required for movement of effectors from specialized infection structures called haustoria into plant cells. This sequence, called RXLR-EER, was recently reported to be required for the translocation of the malarial parasite Plasmodium falciparum into human erythrocytes. These studies suggest that different eukaryotic pathogens use equivalent targeting signals to deliver their effector proteins.

Suggested Citation

  • Stephen C. Whisson & Petra C. Boevink & Lucy Moleleki & Anna O. Avrova & Juan G. Morales & Eleanor M. Gilroy & Miles R. Armstrong & Severine Grouffaud & Pieter van West & Sean Chapman & Ingo Hein & Ia, 2007. "A translocation signal for delivery of oomycete effector proteins into host plant cells," Nature, Nature, vol. 450(7166), pages 115-118, November.
    • Handle: RePEc:nat:nature:v:450:y:2007:i:7166:d:10.1038_nature06203
    DOI: 10.1038/nature06203
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature06203
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature06203?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ana Cruz-Silva & Andreia Figueiredo & Mónica Sebastiana, 2021. "First Insights into the Effect of Mycorrhizae on the Expression of Pathogen Effectors during the Infection of Grapevine with Plasmopara viticola," Sustainability, MDPI, vol. 13(3), pages 1-12, January.
    2. Carly F Summers & Colwyn M Gulliford & Craig H Carlson & Jacquelyn A Lillis & Maryn O Carlson & Lance Cadle-Davidson & David H Gent & Christine D Smart, 2015. "Identification of Genetic Variation between Obligate Plant Pathogens Pseudoperonospora cubensis and P. humuli Using RNA Sequencing and Genotyping-By-Sequencing," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-19, November.
    3. Hui Sheng & Congcong Ai & Cancan Yang & Chunyuan Zhu & Zhe Meng & Fengzhi Wu & Xiaodan Wang & Daolong Dou & Paul F. Morris & Xiuguo Zhang, 2024. "A conserved oomycete effector RxLR23 triggers plant defense responses by targeting ERD15La to release NbNAC68," Nature Communications, Nature, vol. 15(1), pages 1-23, December.
    4. Diane G O Saunders & Joe Win & Liliana M Cano & Les J Szabo & Sophien Kamoun & Sylvain Raffaele, 2012. "Using Hierarchical Clustering of Secreted Protein Families to Classify and Rank Candidate Effectors of Rust Fungi," PLOS ONE, Public Library of Science, vol. 7(1), pages 1-14, January.
    5. Joe Win & Ksenia V Krasileva & Sophien Kamoun & Ken Shirasu & Brian J Staskawicz & Mark J Banfield, 2012. "Sequence Divergent RXLR Effectors Share a Structural Fold Conserved across Plant Pathogenic Oomycete Species," PLOS Pathogens, Public Library of Science, vol. 8(1), pages 1-4, January.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:450:y:2007:i:7166:d:10.1038_nature06203. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.