IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v448y2007i7156d10.1038_nature06033.html
   My bibliography  Save this article

Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells

Author

Listed:
  • Hiroyuki Tezuka

    (Akita University Graduate School of Medicine)

  • Yukiko Abe

    (Akita University Graduate School of Medicine)

  • Makoto Iwata

    (Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University)

  • Hajime Takeuchi

    (Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University)

  • Hiromichi Ishikawa

    (Keio University School of Medicine)

  • Masayuki Matsushita

    (Mitsubishi Kagaku Institute of Life Sciences)

  • Tetsuo Shiohara

    (Kyorin University School of Medicine)

  • Shizuo Akira

    (Research Institute for Microbial Diseases, Osaka University)

  • Toshiaki Ohteki

    (Akita University Graduate School of Medicine)

Abstract

Immunoglobulin-A (IgA) is the main immunoglobulin found in mucous sectretions. B cell class-switch recombination to IgA in mucosa-associated tissues is regulated by a subset of dendritic cells which produce TNF-α and inducible nitric oxide in response to the recognition of commensal bacteria by toll-like receptors

Suggested Citation

  • Hiroyuki Tezuka & Yukiko Abe & Makoto Iwata & Hajime Takeuchi & Hiromichi Ishikawa & Masayuki Matsushita & Tetsuo Shiohara & Shizuo Akira & Toshiaki Ohteki, 2007. "Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells," Nature, Nature, vol. 448(7156), pages 929-933, August.
    • Handle: RePEc:nat:nature:v:448:y:2007:i:7156:d:10.1038_nature06033
    DOI: 10.1038/nature06033
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature06033
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature06033?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Weizhu Zhao & Yanfei Jia & Guangyu Sun & Haiying Yang & Luguang Liu & Xianlin Qu & Jishuang Ding & Hang Yu & Botao Xu & Siwei Zhao & Ligang Xing & Jie Chai, 2023. "Single-cell analysis of gastric signet ring cell carcinoma reveals cytological and immune microenvironment features," Nature Communications, Nature, vol. 14(1), pages 1-15, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:448:y:2007:i:7156:d:10.1038_nature06033. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.