IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v440y2006i7084d10.1038_nature04589.html
   My bibliography  Save this article

Analysis of a RanGTP-regulated gradient in mitotic somatic cells

Author

Listed:
  • Petr Kaláb

    (University of California)

  • Arnd Pralle

    (University of California)

  • Ehud Y. Isacoff

    (University of California)

  • Rebecca Heald

    (University of California)

  • Karsten Weis

    (University of California)

Abstract

A fluorescence resonance energy transfer biosensor called Rango enables examination of the Ran–importin-β system in cells. Small changes in RanGTP concentration tip the balance between positive and negative mitotic regulators, thereby promoting spindle assembly and function.

Suggested Citation

  • Petr Kaláb & Arnd Pralle & Ehud Y. Isacoff & Rebecca Heald & Karsten Weis, 2006. "Analysis of a RanGTP-regulated gradient in mitotic somatic cells," Nature, Nature, vol. 440(7084), pages 697-701, March.
    • Handle: RePEc:nat:nature:v:440:y:2006:i:7084:d:10.1038_nature04589
    DOI: 10.1038/nature04589
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature04589
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature04589?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Bernardo Gouveia & Sagar U. Setru & Matthew R. King & Aaron Hamlin & Howard A. Stone & Joshua W. Shaevitz & Sabine Petry, 2023. "Acentrosomal spindles assemble from branching microtubule nucleation near chromosomes in Xenopus laevis egg extract," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Ai Kiyomitsu & Toshiya Nishimura & Shiang Jyi Hwang & Satoshi Ansai & Masato T. Kanemaki & Minoru Tanaka & Tomomi Kiyomitsu, 2024. "Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos," Nature Communications, Nature, vol. 15(1), pages 1-19, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:440:y:2006:i:7084:d:10.1038_nature04589. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.