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Frontal and stealth attack strategies in microbial pathogenesis

Author

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  • D. Scott Merrell

    (Uniformed Services University of the Health Sciences)

  • Stanley Falkow

    (Stanford School of Medicine)

Abstract

Interactions between microbes and human hosts can range from a benign, even symbiotic collaboration to a competition that may turn fatal — resulting in death of the host, the microbe or both. Despite advances that have been made over the past decades in understanding microbial pathogens, more people worldwide still die every year from infectious disease than from any other cause. This highlights the relevance of continuing to probe the mechanisms used by microorganisms to cause disease, and emphasizes the need for new model systems to advance our understanding of host–pathogen interactions.

Suggested Citation

  • D. Scott Merrell & Stanley Falkow, 2004. "Frontal and stealth attack strategies in microbial pathogenesis," Nature, Nature, vol. 430(6996), pages 250-256, July.
    • Handle: RePEc:nat:nature:v:430:y:2004:i:6996:d:10.1038_nature02760
    DOI: 10.1038/nature02760
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    Cited by:

    1. Elise Vaumourin & Patrick Gasqui & Jean-Philippe Buffet & Jean-Louis Chapuis & Benoît Pisanu & Elisabeth Ferquel & Muriel Vayssier-Taussat & Gwenaël Vourc’h, 2013. "A Probabilistic Model in Cross-Sectional Studies for Identifying Interactions between Two Persistent Vector-Borne Pathogens in Reservoir Populations," PLOS ONE, Public Library of Science, vol. 8(6), pages 1-9, June.

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