IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v421y2003i6921d10.1038_nature01410.html
   My bibliography  Save this article

The digital code of DNA

Author

Listed:
  • Leroy Hood

    (Institute for Systems Biology)

  • David Galas

    (Keck Graduate Institute of Applied Sciences)

Abstract

The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information — the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.

Suggested Citation

  • Leroy Hood & David Galas, 2003. "The digital code of DNA," Nature, Nature, vol. 421(6921), pages 444-448, January.
  • Handle: RePEc:nat:nature:v:421:y:2003:i:6921:d:10.1038_nature01410
    DOI: 10.1038/nature01410
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature01410
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1038/nature01410?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Dan Frumkin & Adam Wasserstrom & Shai Kaplan & Uriel Feige & Ehud Shapiro, 2005. "Genomic Variability within an Organism Exposes Its Cell Lineage Tree," PLOS Computational Biology, Public Library of Science, vol. 1(5), pages 1-13, October.
    2. Luca Marchetti & Rosario Lombardo & Corrado Priami, 2017. "HSimulator: Hybrid Stochastic/Deterministic Simulation of Biochemical Reaction Networks," Complexity, Hindawi, vol. 2017, pages 1-12, December.
    3. Dana Cohen, 2022. "General Designs Reveal a Purine-Pyrimidine Structural Code in Human DNA," Mathematics, MDPI, vol. 10(15), pages 1-20, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:421:y:2003:i:6921:d:10.1038_nature01410. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.