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Nature, nurture and human disease

Author

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  • Aravinda Chakravarti

    (McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine)

  • Peter Little

    (School of Biotechnology and Biomolecular Sciences, University of New South Wales)

Abstract

What has been learnt about individual human biology and common diseases 50 years on from the discovery of the structure of DNA? Unfortunately the double helix has not, so far, revealed as much as one would have hoped. The primary reason is an inability to determine how nurture fits into the DNA paradigm. We argue here that the environment exerts its influence at the DNA level and so will need to be understood before the underlying causal factors of common human diseases can be fully recognized.

Suggested Citation

  • Aravinda Chakravarti & Peter Little, 2003. "Nature, nurture and human disease," Nature, Nature, vol. 421(6921), pages 412-414, January.
    • Handle: RePEc:nat:nature:v:421:y:2003:i:6921:d:10.1038_nature01401
    DOI: 10.1038/nature01401
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    Cited by:

    1. Raman Deep Pattanayak & Rajesh Sagar, 2012. "A qualitative study of perceptions related to family risk of bipolar disorder among patients and family members from India," International Journal of Social Psychiatry, , vol. 58(5), pages 463-469, September.

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