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Hiding messages in DNA microdots

Author

Listed:
  • Catherine Taylor Clelland

    (Mount Sinai School of Medicine)

  • Viviana Risca

    (Paul D. Schreiber High School)

  • Carter Bancroft

    (Mount Sinai School of Medicine)

Abstract

The microdot is a means of concealing messages (steganography)1 that was developed by Professor Zapp and used by German spies in the Second World War to transmit secret information2. A microdot (“the enemy's masterpiece of espionage”2) was a greatly reduced photograph of a typewritten page that was pasted over a full stop in an innocuous letter2. We have taken the microdot a step further and developed a DNA-based, doubly steganographic technique for sending secret messages. A DNA-encoded message is first camouflaged within the enormous complexity of human genomic DNA and then further concealed by confining this sample to a microdot.

Suggested Citation

  • Catherine Taylor Clelland & Viviana Risca & Carter Bancroft, 1999. "Hiding messages in DNA microdots," Nature, Nature, vol. 399(6736), pages 533-534, June.
    • Handle: RePEc:nat:nature:v:399:y:1999:i:6736:d:10.1038_21092
    DOI: 10.1038/21092
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    Cited by:

    1. Cheuk Chi A. Ng & Wai Man Tam & Haidi Yin & Qian Wu & Pui-Kin So & Melody Yee-Man Wong & Francis C. M. Lau & Zhong-Ping Yao, 2021. "Data storage using peptide sequences," Nature Communications, Nature, vol. 12(1), pages 1-10, December.
    2. Adam Kuzdraliński & Marek Miśkiewicz & Hubert Szczerba & Wojciech Mazurczyk & Jeff Nivala & Bogdan Księżopolski, 2023. "Unlocking the potential of DNA-based tagging: current market solutions and expanding horizons," Nature Communications, Nature, vol. 14(1), pages 1-7, December.
    3. Malcolm Miao Geng Sow & Zheng Zhang & Chorng Haur Sow & Sharon Xiaodai Lim, 2023. "Upcycling fish scales through heating for steganography and Rhodamine B adsorption application," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

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