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Molecular diagnostics in medical mycology

Author

Listed:
  • Brian L. Wickes

    (The University of Texas Health Science Center at San Antonio)

  • Nathan P. Wiederhold

    (The University of Texas Health Science Center at San Antonio)

Abstract

Diagnosing fungal infections poses a number of unique problems, including a decline in expertise needed for identifying fungi, and a reduced number of instruments and assays specific for fungal identification compared to that of bacteria and viruses.These problems are exacerbated by the fact that patients with fungal infections are often immunosuppressed, which predisposes to infections from both commonly and rarely seen fungi. In this review, we discuss current and future molecular technologies used for fungal identification, and some of the problems associated with development and implementation of these technologies in today’s clinical microbiology laboratories.

Suggested Citation

  • Brian L. Wickes & Nathan P. Wiederhold, 2018. "Molecular diagnostics in medical mycology," Nature Communications, Nature, vol. 9(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-07556-5
    DOI: 10.1038/s41467-018-07556-5
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    Cited by:

    1. Awatif A. Elegami & El Amin I. Elnima & Gamal E.B. El Ghazali, 2022. "In-vitro Antifungal efficacy of Some Medicinal Plants," International Journal of Sciences, Office ijSciences, vol. 11(10), pages 10-15, October.
    2. Neil A. R. Gow & Carolyn Johnson & Judith Berman & Alix T. Coste & Christina A. Cuomo & David S. Perlin & Tihana Bicanic & Thomas S. Harrison & Nathan Wiederhold & Mike Bromley & Tom Chiller & Keegan , 2022. "The importance of antimicrobial resistance in medical mycology," Nature Communications, Nature, vol. 13(1), pages 1-12, December.

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