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Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids

Author

Listed:
  • Haishui Huang

    (Harvard Medical School and Shriners Hospitals for Children)

  • Martin L. Yarmush

    (Harvard Medical School and Shriners Hospitals for Children
    Rutgers University)

  • O. Berk Usta

    (Harvard Medical School and Shriners Hospitals for Children)

Abstract

Supercooling of aqueous solutions is a fundamentally and practically important physical phenomenon with numerous applications in biopreservation and beyond. Under normal conditions, heterogeneous nucleation mechanisms critically prohibit the simultaneous long-term (> 1 week), large volume (> 1 ml), and low temperatures (

Suggested Citation

  • Haishui Huang & Martin L. Yarmush & O. Berk Usta, 2018. "Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids," Nature Communications, Nature, vol. 9(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-05636-0
    DOI: 10.1038/s41467-018-05636-0
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    Cited by:

    1. Matthew J. Powell-Palm & E. Michael Henley & Anthony N. Consiglio & Claire Lager & Brooke Chang & Riley Perry & Kendall Fitzgerald & Jonathan Daly & Boris Rubinsky & Mary Hagedorn, 2023. "Cryopreservation and revival of Hawaiian stony corals using isochoric vitrification," Nature Communications, Nature, vol. 14(1), pages 1-11, December.

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