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Go/No-Go task engagement enhances population representation of target stimuli in primary auditory cortex

Author

Listed:
  • Sophie Bagur

    (École Supérieure de Physique et de Chimie Industrielles de la Ville de Paris)

  • Martin Averseng

    (PSL Research University, CNRS)

  • Diego Elgueda

    (University of Maryland in College Park)

  • Stephen David

    (Oregon Health & Science University)

  • Jonathan Fritz

    (University of Maryland in College Park)

  • Pingbo Yin

    (University of Maryland in College Park)

  • Shihab Shamma

    (PSL Research University, CNRS
    University of Maryland in College Park)

  • Yves Boubenec

    (PSL Research University, CNRS)

  • Srdjan Ostojic

    (PSL Research University)

Abstract

Primary sensory cortices are classically considered to extract and represent stimulus features, while association and higher-order areas are thought to carry information about stimulus meaning. Here we show that this information can in fact be found in the neuronal population code of the primary auditory cortex (A1). A1 activity was recorded in awake ferrets while they either passively listened or actively discriminated stimuli in a range of Go/No-Go paradigms, with different sounds and reinforcements. Population-level dimensionality reduction techniques reveal that task engagement induces a shift in stimulus encoding from a sensory to a behaviorally driven representation that specifically enhances the target stimulus in all paradigms. This shift partly relies on task-engagement-induced changes in spontaneous activity. Altogether, we show that A1 population activity bears strong similarities to frontal cortex responses. These findings indicate that primary sensory cortices implement a crucial change in the structure of population activity to extract task-relevant information during behavior.

Suggested Citation

  • Sophie Bagur & Martin Averseng & Diego Elgueda & Stephen David & Jonathan Fritz & Pingbo Yin & Shihab Shamma & Yves Boubenec & Srdjan Ostojic, 2018. "Go/No-Go task engagement enhances population representation of target stimuli in primary auditory cortex," Nature Communications, Nature, vol. 9(1), pages 1-16, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-04839-9
    DOI: 10.1038/s41467-018-04839-9
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    Cited by:

    1. Joao Barbosa & Rémi Proville & Chris C. Rodgers & Michael R. DeWeese & Srdjan Ostojic & Yves Boubenec, 2023. "Early selection of task-relevant features through population gating," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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