IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v8y2017i1d10.1038_ncomms15602.html
   My bibliography  Save this article

Perirhinal firing patterns are sustained across large spatial segments of the task environment

Author

Listed:
  • Jeroen J. Bos

    (Swammerdam Institute for Life Sciences, Center for Neuroscience, Faculty of Science, University of Amsterdam
    Research Priority Program Brain and Cognition, University of Amsterdam)

  • Martin Vinck

    (Swammerdam Institute for Life Sciences, Center for Neuroscience, Faculty of Science, University of Amsterdam
    Ernst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society)

  • Laura A. van Mourik-Donga

    (Swammerdam Institute for Life Sciences, Center for Neuroscience, Faculty of Science, University of Amsterdam
    Research Priority Program Brain and Cognition, University of Amsterdam)

  • Jadin C. Jackson

    (Swammerdam Institute for Life Sciences, Center for Neuroscience, Faculty of Science, University of Amsterdam
    Medtronic)

  • Menno P. Witter

    (Kavli Institute for Systems Neuroscience, Centre for Neural Computation, Norwegian University of Science and Technology)

  • Cyriel M. A. Pennartz

    (Swammerdam Institute for Life Sciences, Center for Neuroscience, Faculty of Science, University of Amsterdam
    Research Priority Program Brain and Cognition, University of Amsterdam)

Abstract

Spatial navigation and memory depend on the neural coding of an organism’s location. Fine-grained coding of location is thought to depend on the hippocampus. Likewise, animals benefit from knowledge parsing their environment into larger spatial segments, which are relevant for task performance. Here we investigate how such knowledge may be coded, and whether this occurs in structures in the temporal lobe, supplying cortical inputs to the hippocampus. We found that neurons in the perirhinal cortex of rats generate sustained firing patterns that discriminate large segments of the task environment. This contrasted to transient firing in hippocampus and sensory neocortex. These spatially extended patterns were not explained by task variables or temporally discrete sensory stimuli. Previously it has been suggested that the perirhinal cortex is part of a pathway processing object, but not spatial information. Our results indicate a greater complexity of neural coding than captured by this dichotomy.

Suggested Citation

  • Jeroen J. Bos & Martin Vinck & Laura A. van Mourik-Donga & Jadin C. Jackson & Menno P. Witter & Cyriel M. A. Pennartz, 2017. "Perirhinal firing patterns are sustained across large spatial segments of the task environment," Nature Communications, Nature, vol. 8(1), pages 1-12, August.
    • Handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms15602
    DOI: 10.1038/ncomms15602
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms15602
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/ncomms15602?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Lukas Grossberger & Francesco P Battaglia & Martin Vinck, 2018. "Unsupervised clustering of temporal patterns in high-dimensional neuronal ensembles using a novel dissimilarity measure," PLOS Computational Biology, Public Library of Science, vol. 14(7), pages 1-34, July.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms15602. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.