IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v8y2017i1d10.1038_ncomms14652.html
   My bibliography  Save this article

Hippocampal and prefrontal processing of network topology to simulate the future

Author

Listed:
  • Amir-Homayoun Javadi

    (School of Psychology, University of Kent)

  • Beatrix Emo

    (Chair of Cognitive Science
    Bartlett School of Architecture and Design, University College London)

  • Lorelei R. Howard

    (Aging and Cognition Research Group, German Center for Neurodegenerative Diseases (DZNE))

  • Fiona E. Zisch

    (UCL Institute of Behavioural Neuroscience, University College London
    Bartlett School of Architecture and Design, University College London)

  • Yichao Yu

    (UCL Centre for Advanced Biomedical Imaging, University College London)

  • Rebecca Knight

    (School of Psychology, University of Hertfordshire)

  • Joao Pinelo Silva

    (University of Bahrain 840)

  • Hugo J. Spiers

    (UCL Institute of Behavioural Neuroscience, University College London)

Abstract

Topological networks lie at the heart of our cities and social milieu. However, it remains unclear how and when the brain processes topological structures to guide future behaviour during everyday life. Using fMRI in humans and a simulation of London (UK), here we show that, specifically when new streets are entered during navigation of the city, right posterior hippocampal activity indexes the change in the number of local topological connections available for future travel and right anterior hippocampal activity reflects global properties of the street entered. When forced detours require re-planning of the route to the goal, bilateral inferior lateral prefrontal activity scales with the planning demands of a breadth-first search of future paths. These results help shape models of how hippocampal and prefrontal regions support navigation, planning and future simulation.

Suggested Citation

  • Amir-Homayoun Javadi & Beatrix Emo & Lorelei R. Howard & Fiona E. Zisch & Yichao Yu & Rebecca Knight & Joao Pinelo Silva & Hugo J. Spiers, 2017. "Hippocampal and prefrontal processing of network topology to simulate the future," Nature Communications, Nature, vol. 8(1), pages 1-11, April.
    • Handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms14652
    DOI: 10.1038/ncomms14652
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/ncomms14652
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/ncomms14652?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Susanne Ulrich & Eva Grill & Virginia L Flanagin, 2019. "Who gets lost and why: A representative cross-sectional survey on sociodemographic and vestibular determinants of wayfinding strategies," PLOS ONE, Public Library of Science, vol. 14(1), pages 1-16, January.
    2. Benhamou, Salima, 2022. "Les transformations du travail et de l’emploi à l’ère de l’Intelligence artificielle: Évaluation, illustrations et interrogations," Documentos de Proyectos 48529, Naciones Unidas Comisión Económica para América Latina y el Caribe (CEPAL).

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:8:y:2017:i:1:d:10.1038_ncomms14652. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.