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Transgenerational gene silencing causes gain of virulence in a plant pathogen

Author

Listed:
  • Dinah Qutob

    (Agriculture and Agri-Food Canada)

  • B. Patrick Chapman

    (Agriculture and Agri-Food Canada)

  • Mark Gijzen

    (Agriculture and Agri-Food Canada)

Abstract

Avirulence (Avr) genes of plant pathogens encode effector proteins that trigger immunity in plants carrying appropriate resistance (R) genes. The Phytophthora sojae Avr3a gene displays allelic variation in messenger RNA transcript levels. P. sojae strains with detectable Avr3a gene transcripts are avirulent on plants carrying the R-gene Rps3a, whereas strains lacking Avr3a mRNA escape detection by Rps3a and are virulent. Here we show non-Mendelian interactions between naturally occurring Avr3a alleles that result in transgenerational gene silencing, and we identify small RNA molecules of 25 nucleotides that are abundant in gene-silenced strains but not in strains with Avr3a mRNA. This example of transgenerational gene silencing is exceptional because it is naturally occurring and results in gain of virulence in a pathogenic organism.

Suggested Citation

  • Dinah Qutob & B. Patrick Chapman & Mark Gijzen, 2013. "Transgenerational gene silencing causes gain of virulence in a plant pathogen," Nature Communications, Nature, vol. 4(1), pages 1-6, June.
    • Handle: RePEc:nat:natcom:v:4:y:2013:i:1:d:10.1038_ncomms2354
    DOI: 10.1038/ncomms2354
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    Cited by:

    1. Austin G. McCoy & Richard R. Belanger & Carl A. Bradley & Daniel G. Cerritos-Garcia & Vinicius C. Garnica & Loren J. Giesler & Pablo E. Grijalba & Eduardo Guillin & Maria A. Henriquez & Yong Min Kim &, 2023. "A global-temporal analysis on Phytophthora sojae resistance-gene efficacy," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

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