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Capturing the essence of folding and functions of biomolecules using coarse-grained models

Author

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  • Changbong Hyeon

    (School of Computational Sciences, Korea Institute for Advanced Study)

  • D. Thirumalai

    (Biophysics Program, Institute For Physical Science and Technology, University of Maryland)

Abstract

Coarse-grained models can be used to study the folding of biological macromolecules such as DNA, RNA and proteins. In this Review, Hyeon and Thirumalai describe recent advances in the use of these theoretical models to describe dynamic processes in biology.

Suggested Citation

  • Changbong Hyeon & D. Thirumalai, 2011. "Capturing the essence of folding and functions of biomolecules using coarse-grained models," Nature Communications, Nature, vol. 2(1), pages 1-11, September.
    • Handle: RePEc:nat:natcom:v:2:y:2011:i:1:d:10.1038_ncomms1481
    DOI: 10.1038/ncomms1481
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    Cited by:

    1. Andreas Walbrun & Tianhe Wang & Michael Matthies & Petr Šulc & Friedrich C. Simmel & Matthias Rief, 2024. "Single-molecule force spectroscopy of toehold-mediated strand displacement," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

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