IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v15y2024i1d10.1038_s41467-024-54306-x.html
   My bibliography  Save this article

The commitment of the human cell atlas to humanity

Author

Listed:
  • Ido Amit

    (Weizmann Institute of Science)

  • Kristin Ardlie

    (Broad Institute)

  • Fabiana Arzuaga

    (Technology and Productive Innovation)

  • Gordon Awandare

    (University of Ghana)

  • Gary Bader

    (University of Toronto)

  • Alexander Bernier

    (McGill University)

  • Piero Carninci

    (RIKEN Center for Integrative Medical Sciences
    Human Technopole)

  • Stacey Donnelly

    (Broad Institute)

  • Roland Eils

    (BIH@Charité - Center for Digital Health)

  • Alistair R. R. Forrest

    (Harry Perkins Institute of Medical Research)

  • Henry T. Greely

    (Stanford University)

  • Roderic Guigo

    (Universitat Pompeu Fabra)

  • Nir Hacohen

    (Mass General Hospital)

  • Muzlifah Haniffa

    (Hinxton)

  • Emily Sarah Kirby

    (McGill University)

  • Bartha Maria Knoppers

    (McGill University)

  • Arnold Kriegstein

    (University of California)

  • Ed S. Lein

    (University of Washington)

  • Sten Linnarsson

    (Karolinska Institute)

  • Partha P. Majumder

    (John C. Martin Centre for Liver Research & Innovation
    Indian Statistical Institute)

  • Miriam Merad

    (Mount Sinai School of Medicine)

  • Kerstin Meyer

    (Hinxton)

  • Musa M. Mhlanga

    (RIMLS-Science)

  • Garry Nolan

    (Stanford University School of Medicine)

  • Ntobeko A. B. Ntusi

    (and SAMRC Extramural Unit on Intersection of Noncommunicable Diseases and Infectious Diseases)

  • Dana Pe’er

    (Memorial Sloan Kettering Cancer Center)

  • Shyam Prabhakar

    (Technology and Research (A*STAR))

  • Maili Raven-Adams

    (Global Alliance for Genomics and Health, Wellcome Sanger Institute)

  • Aviv Regev

    (Human Cell Atlas)

  • Orit Rozenblatt-Rosen

    (Human Cell Atlas)

  • Senjuti Saha

    (Child Health Research Foundation)

  • Andrea Saltzman

    (Broad Institute)

  • Alex K. Shalek

    (Broad Institute
    Massachusetts Institute of Technology)

  • Jay W. Shin

    (Technology and Research (A*STAR))

  • Henk Stunnenberg

    (Radboud Institute for Molecular Life Sciences)

  • Sarah A. Teichmann

    (Hinxton)

  • Timothy Tickle

    (Broad Institute)

  • Alexandra-Chloe Villani

    (Massachusetts General Hospital)

  • Christine Wells

    (University of Melbourne)

  • Barbara Wold

    (California Institute of Technology)

  • Huanming Yang

    (BGI-Shenzhen)

  • Xiaowei Zhuang

    (Harvard University)

Abstract

The Human Cell Atlas (HCA) is a global partnership “to create comprehensive reference maps of all human cells—the fundamental units of life – as a basis for both understanding human health and diagnosing, monitoring, and treating disease.” ( https://www.humancellatlas.org/ ) The atlas shall characterize cells from diverse individuals across the globe to better understand human biology. HCA proactively considers the priorities of, and benefits accrued to, contributing communities. Here, we lay out principles and action items that have been adopted to affirm HCA’s commitment to equity so that the atlas is beneficial to all of humanity.

Suggested Citation

  • Ido Amit & Kristin Ardlie & Fabiana Arzuaga & Gordon Awandare & Gary Bader & Alexander Bernier & Piero Carninci & Stacey Donnelly & Roland Eils & Alistair R. R. Forrest & Henry T. Greely & Roderic Gui, 2024. "The commitment of the human cell atlas to humanity," Nature Communications, Nature, vol. 15(1), pages 1-7, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-54306-x
    DOI: 10.1038/s41467-024-54306-x
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-024-54306-x
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/s41467-024-54306-x?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Carlos D. Bustamante & Francisco M. De La Vega & Esteban G. Burchard, 2011. "Genomics for the world," Nature, Nature, vol. 475(7355), pages 163-165, July.
    2. Clare Bycroft & Colin Freeman & Desislava Petkova & Gavin Band & Lloyd T. Elliott & Kevin Sharp & Allan Motyer & Damjan Vukcevic & Olivier Delaneau & Jared O’Connell & Adrian Cortes & Samantha Welsh &, 2018. "The UK Biobank resource with deep phenotyping and genomic data," Nature, Nature, vol. 562(7726), pages 203-209, October.
    3. Alice B. Popejoy & Stephanie M. Fullerton, 2016. "Genomics is failing on diversity," Nature, Nature, vol. 538(7624), pages 161-164, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Brandy M Mapes & Christopher S Foster & Sheila V Kusnoor & Marcia I Epelbaum & Mona AuYoung & Gwynne Jenkins & Maria Lopez-Class & Dara Richardson-Heron & Ahmed Elmi & Karl Surkan & Robert M Cronin & , 2020. "Diversity and inclusion for the All of Us research program: A scoping review," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-14, July.
    2. Nadine R. Caron & Wilf Adam & Kate Anderson & Brooke T. Boswell & Meck Chongo & Viktor Deineko & Alexanne Dick & Shannon E. Hall & Jessica T. Hatcher & Patricia Howard & Megan Hunt & Kevin Linn & Ashl, 2023. "Partnering with First Nations in Northern British Columbia Canada to Reduce Inequity in Access to Genomic Research," IJERPH, MDPI, vol. 20(10), pages 1-31, May.
    3. Alesha A. Hatton & Fei-Fei Cheng & Tian Lin & Ren-Juan Shen & Jie Chen & Zhili Zheng & Jia Qu & Fan Lyu & Sarah E. Harris & Simon R. Cox & Zi-Bing Jin & Nicholas G. Martin & Dongsheng Fan & Grant W. M, 2024. "Genetic control of DNA methylation is largely shared across European and East Asian populations," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    4. Jiacheng Miao & Hanmin Guo & Gefei Song & Zijie Zhao & Lin Hou & Qiongshi Lu, 2023. "Quantifying portable genetic effects and improving cross-ancestry genetic prediction with GWAS summary statistics," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    5. Kevin L Keys & Angel C Y Mak & Marquitta J White & Walter L Eckalbar & Andrew W Dahl & Joel Mefford & Anna V Mikhaylova & María G Contreras & Jennifer R Elhawary & Celeste Eng & Donglei Hu & Scott Hun, 2020. "On the cross-population generalizability of gene expression prediction models," PLOS Genetics, Public Library of Science, vol. 16(8), pages 1-28, August.
    6. Brieuc Lehmann & Maxine Mackintosh & Gil McVean & Chris Holmes, 2023. "Optimal strategies for learning multi-ancestry polygenic scores vary across traits," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    7. Matteo Di Scipio & Mohammad Khan & Shihong Mao & Michael Chong & Conor Judge & Nazia Pathan & Nicolas Perrot & Walter Nelson & Ricky Lali & Shuang Di & Robert Morton & Jeremy Petch & Guillaume Paré, 2023. "A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    8. Heng Du & Lei Zhou & Zhen Liu & Yue Zhuo & Meilin Zhang & Qianqian Huang & Shiyu Lu & Kai Xing & Li Jiang & Jian-Feng Liu, 2024. "The 1000 Chinese Indigenous Pig Genomes Project provides insights into the genomic architecture of pigs," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    9. Vincent Michaud & Eulalie Lasseaux & David J. Green & Dave T. Gerrard & Claudio Plaisant & Tomas Fitzgerald & Ewan Birney & Benoît Arveiler & Graeme C. Black & Panagiotis I. Sergouniotis, 2022. "The contribution of common regulatory and protein-coding TYR variants to the genetic architecture of albinism," Nature Communications, Nature, vol. 13(1), pages 1-8, December.
    10. Natalie DeForest & Yuqi Wang & Zhiyi Zhu & Jacqueline S. Dron & Ryan Koesterer & Pradeep Natarajan & Jason Flannick & Tiffany Amariuta & Gina M. Peloso & Amit R. Majithia, 2024. "Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    11. Dick Schijven & Sourena Soheili-Nezhad & Simon E. Fisher & Clyde Francks, 2024. "Exome-wide analysis implicates rare protein-altering variants in human handedness," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    12. Shahram Bahrami & Kaja Nordengen & Jaroslav Rokicki & Alexey A. Shadrin & Zillur Rahman & Olav B. Smeland & Piotr P. Jaholkowski & Nadine Parker & Pravesh Parekh & Kevin S. O’Connell & Torbjørn Elvsås, 2024. "The genetic landscape of basal ganglia and implications for common brain disorders," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    13. Sylvia Hartmann & Summaira Yasmeen & Benjamin M. Jacobs & Spiros Denaxas & Munir Pirmohamed & Eric R. Gamazon & Mark J. Caulfield & Harry Hemingway & Maik Pietzner & Claudia Langenberg, 2023. "ADRA2A and IRX1 are putative risk genes for Raynaud’s phenomenon," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    14. Mit Shah & Marco H. A. Inácio & Chang Lu & Pierre-Raphaël Schiratti & Sean L. Zheng & Adam Clement & Antonio Marvao & Wenjia Bai & Andrew P. King & James S. Ware & Martin R. Wilkins & Johanna Mielke &, 2023. "Environmental and genetic predictors of human cardiovascular ageing," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    15. Zhaotong Lin & Wei Pan, 2024. "A robust cis-Mendelian randomization method with application to drug target discovery," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    16. Zhening Liu & Hangkai Huang & Jiarong Xie & Yingying Xu & Chengfu Xu, 2024. "Circulating fatty acids and risk of hepatocellular carcinoma and chronic liver disease mortality in the UK Biobank," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    17. Junqing Xie & Shuo Feng & Xintong Li & Ester Gea-Mallorquí & Albert Prats-Uribe & Dani Prieto-Alhambra, 2022. "Comparative effectiveness of the BNT162b2 and ChAdOx1 vaccines against Covid-19 in people over 50," Nature Communications, Nature, vol. 13(1), pages 1-8, December.
    18. Rongtao Jiang & Stephanie Noble & Matthew Rosenblatt & Wei Dai & Jean Ye & Shu Liu & Shile Qi & Vince D. Calhoun & Jing Sui & Dustin Scheinost, 2024. "The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    19. Michel S. Naslavsky & Marilia O. Scliar & Guilherme L. Yamamoto & Jaqueline Yu Ting Wang & Stepanka Zverinova & Tatiana Karp & Kelly Nunes & José Ricardo Magliocco Ceroni & Diego Lima Carvalho & Carlo, 2022. "Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    20. Romain Fournier & Zoi Tsangalidou & David Reich & Pier Francesco Palamara, 2023. "Haplotype-based inference of recent effective population size in modern and ancient DNA samples," Nature Communications, Nature, vol. 14(1), pages 1-13, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-54306-x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.