Integrin β3 directly inhibits the Gα13-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis
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DOI: 10.1038/s41467-023-40531-3
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- Liang Zhu & Jun Yang & Thomas Bromberger & Ashley Holly & Fan Lu & Huan Liu & Kevin Sun & Sarah Klapproth & Jamila Hirbawi & Tatiana V. Byzova & Edward F. Plow & Markus Moser & Jun Qin, 2017. "Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation," Nature Communications, Nature, vol. 8(1), pages 1-12, December.
- Bo Shen & Xiaojuan Zhao & Kelly A. O’Brien & Aleksandra Stojanovic-Terpo & M. Keegan Delaney & Kyungho Kim & Jaehyung Cho & Stephen C.-T. Lam & Xiaoping Du, 2013. "A directional switch of integrin signalling and a new anti-thrombotic strategy," Nature, Nature, vol. 503(7474), pages 131-135, November.
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