Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-022-34095-x
Download full text from publisher
References listed on IDEAS
- Elizabeth Haythorne & Maria Rohm & Martijn Bunt & Melissa F. Brereton & Andrei I. Tarasov & Thomas S. Blacker & Gregor Sachse & Mariana Silva dos Santos & Raul Terron Exposito & Simon Davis & Otto Bab, 2019. "Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells," Nature Communications, Nature, vol. 10(1), pages 1-17, December.
- Chen-Song Zhang & Simon A. Hawley & Yue Zong & Mengqi Li & Zhichao Wang & Alexander Gray & Teng Ma & Jiwen Cui & Jin-Wei Feng & Mingjiang Zhu & Yu-Qing Wu & Terytty Yang Li & Zhiyun Ye & Shu-Yong Lin , 2017. "Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK," Nature, Nature, vol. 548(7665), pages 112-116, August.
- Pierre Maechler & Claes B. Wollheim, 2001. "Mitochondrial function in normal and diabetic β-cells," Nature, Nature, vol. 414(6865), pages 807-812, December.
- Melissa F. Brereton & Michaela Iberl & Kenju Shimomura & Quan Zhang & Alice E. Adriaenssens & Peter Proks & Ioannis I. Spiliotis & William Dace & Katia K. Mattis & Reshma Ramracheya & Fiona M. Gribble, 2014. "Reversible changes in pancreatic islet structure and function produced by elevated blood glucose," Nature Communications, Nature, vol. 5(1), pages 1-11, December.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Vaibhav Sidarala & Jie Zhu & Elena Levi-D’Ancona & Gemma L. Pearson & Emma C. Reck & Emily M. Walker & Brett A. Kaufman & Scott A. Soleimanpour, 2022. "Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
- Danielle L. Schmitt & Stephanie D. Curtis & Anne C. Lyons & Jin-fan Zhang & Mingyuan Chen & Catherine Y. He & Sohum Mehta & Reuben J. Shaw & Jin Zhang, 2022. "Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Chen Weng & Anniya Gu & Shanshan Zhang & Leina Lu & Luxin Ke & Peidong Gao & Xiaoxiao Liu & Yuntong Wang & Peinan Hu & Dylan Plummer & Elise MacDonald & Saixian Zhang & Jiajia Xi & Sisi Lai & Konstant, 2023. "Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Javier Moral-Sanz & Sophronia A. Lewis & Sandy MacMillan & Marco Meloni & Heather McClafferty & Benoit Viollet & Marc Foretz & Jorge del-Pozo & A. Mark Evans, 2022. "AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Yaqiong Li & Zhipeng Niu & Jichao Yang & Xuke Yang & Yukun Chen & Yingying Li & Xiaohan Liang & Jingwen Zhang & Fuqiang Fan & Ping Wu & Chao Peng & Bang Shen, 2023. "Rapid metabolic reprogramming mediated by the AMP-activated protein kinase during the lytic cycle of Toxoplasma gondii," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Jinsook Son & Wen Du & Mark Esposito & Kaavian Shariati & Hongxu Ding & Yibin Kang & Domenico Accili, 2023. "Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Hwee Hui Lau & Nicole A. J. Krentz & Fernando Abaitua & Marta Perez-Alcantara & Jun-Wei Chan & Jila Ajeian & Soumita Ghosh & Yunkyeong Lee & Jing Yang & Swaraj Thaman & Benoite Champon & Han Sun & Alo, 2023. "PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Zhenzhen Zi & Zhuzhen Zhang & Qiang Feng & Chiho Kim & Xu-Dong Wang & Philipp E. Scherer & Jinming Gao & Beth Levine & Yonghao Yu, 2022. "Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Yingfeng Tu & Qin Yang & Min Tang & Li Gao & Yuanhao Wang & Jiuqiang Wang & Zhe Liu & Xiaoyu Li & Lejiao Mao & Rui zhen Jia & Yuan Wang & Tie-shan Tang & Pinglong Xu & Yan Liu & Lunzhi Dai & Da Jia, 2024. "TBC1D23 mediates Golgi-specific LKB1 signaling," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
- Yu-Te Yeh & Chandan Sona & Xin Yan & Yunxiao Li & Adrija Pathak & Mark I. McDermott & Zhigang Xie & Liangwen Liu & Anoop Arunagiri & Yuting Wang & Amaury Cazenave-Gassiot & Adhideb Ghosh & Ferdinand v, 2023. "Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Kibum Kim & Hee Chan Yoo & Byung Gyu Kim & Sulhee Kim & Yulseung Sung & Ina Yoon & Ya Chun Yu & Seung Joon Park & Jong Hyun Kim & Kyungjae Myung & Kwang Yeon Hwang & Sunghoon Kim & Jung Min Han, 2022. "O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-34095-x. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.