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Regional connectivity drove bidirectional transmission of SARS-CoV-2 in the Middle East during travel restrictions

Author

Listed:
  • Edyth Parker

    (The Scripps Research Institute)

  • Catelyn Anderson

    (The Scripps Research Institute)

  • Mark Zeller

    (The Scripps Research Institute)

  • Ahmad Tibi

    (Biolab Diagnostic Laboratories)

  • Jennifer L. Havens

    (University of California San Diego)

  • Geneviève Laroche

    (University of Ottawa)

  • Mehdi Benlarbi

    (University of Ottawa)

  • Ardeshir Ariana

    (University of Ottawa)

  • Refugio Robles-Sikisaka

    (The Scripps Research Institute)

  • Alaa Abdel Latif

    (The Scripps Research Institute)

  • Alexander Watts

    (Bluedot)

  • Abdalla Awidi

    (The University of Jordan
    The University of Jordan)

  • Saied A. Jaradat

    (Jordan University of Science and Technology)

  • Karthik Gangavarapu

    (David Geffen School of Medicine, University of California, Los Angeles)

  • Karthik Ramesh

    (The Scripps Research Institute)

  • Ezra Kurzban

    (The Scripps Research Institute)

  • Nathaniel L. Matteson

    (The Scripps Research Institute)

  • Alvin X. Han

    (University of Amsterdam, Amsterdam Institute for Infection and Immunity)

  • Laura D. Hughes

    (The Scripps Research Institute)

  • Michelle McGraw

    (The Scripps Research Institute)

  • Emily Spencer

    (Scripps Research Translational Institute)

  • Laura Nicholson

    (Scripps Research Translational Institute)

  • Kamran Khan

    (Bluedot)

  • Marc A. Suchard

    (David Geffen School of Medicine, University of California, Los Angeles
    Fielding School of Public Health, University of California, Los Angeles)

  • Joel O. Wertheim

    (University of California San Diego)

  • Shirlee Wohl

    (The Scripps Research Institute)

  • Marceline Côté

    (University of Ottawa)

  • Amid Abdelnour

    (Biolab Diagnostic Laboratories)

  • Kristian G. Andersen

    (The Scripps Research Institute)

  • Issa Abu-Dayyeh

    (Biolab Diagnostic Laboratories
    The University of Jordan)

Abstract

Regional connectivity and land travel have been identified as important drivers of SARS-CoV-2 transmission. However, the generalizability of this finding is understudied outside of well-sampled, highly connected regions. In this study, we investigated the relative contributions of regional and intercontinental connectivity to the source-sink dynamics of SARS-CoV-2 for Jordan and the Middle East. By integrating genomic, epidemiological and travel data we show that the source of introductions into Jordan was dynamic across 2020, shifting from intercontinental seeding in the early pandemic to more regional seeding for the travel restrictions period. We show that land travel, particularly freight transport, drove introduction risk during the travel restrictions period. High regional connectivity and land travel also drove Jordan’s export risk. Our findings emphasize regional connectedness and land travel as drivers of transmission in the Middle East.

Suggested Citation

  • Edyth Parker & Catelyn Anderson & Mark Zeller & Ahmad Tibi & Jennifer L. Havens & Geneviève Laroche & Mehdi Benlarbi & Ardeshir Ariana & Refugio Robles-Sikisaka & Alaa Abdel Latif & Alexander Watts & , 2022. "Regional connectivity drove bidirectional transmission of SARS-CoV-2 in the Middle East during travel restrictions," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-32536-1
    DOI: 10.1038/s41467-022-32536-1
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    1. Thomas Hale & Noam Angrist & Rafael Goldszmidt & Beatriz Kira & Anna Petherick & Toby Phillips & Samuel Webster & Emily Cameron-Blake & Laura Hallas & Saptarshi Majumdar & Helen Tatlow, 2021. "A global panel database of pandemic policies (Oxford COVID-19 Government Response Tracker)," Nature Human Behaviour, Nature, vol. 5(4), pages 529-538, April.
    2. Gytis Dudas & Samuel L. Hong & Barney I. Potter & Sébastien Calvignac-Spencer & Frédéric S. Niatou-Singa & Thais B. Tombolomako & Terence Fuh-Neba & Ulrich Vickos & Markus Ulrich & Fabian H. Leendertz, 2021. "Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
    3. Yvan Butera & Enatha Mukantwari & Maria Artesi & Jeanne d’arc Umuringa & Áine Niamh O’Toole & Verity Hill & Stefan Rooke & Samuel Leandro Hong & Simon Dellicour & Onesphore Majyambere & Sebastien Bont, 2021. "Genomic sequencing of SARS-CoV-2 in Rwanda reveals the importance of incoming travelers on lineage diversity," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    4. Philippe Lemey & Samuel L. Hong & Verity Hill & Guy Baele & Chiara Poletto & Vittoria Colizza & Áine O’Toole & John T. McCrone & Kristian G. Andersen & Michael Worobey & Martha I. Nelson & Andrew Ramb, 2020. "Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2," Nature Communications, Nature, vol. 11(1), pages 1-14, December.
    5. Danielle Miller & Michael A. Martin & Noam Harel & Omer Tirosh & Talia Kustin & Moran Meir & Nadav Sorek & Shiraz Gefen-Halevi & Sharon Amit & Olesya Vorontsov & Avraham Shaag & Dana Wolf & Avi Peretz, 2020. "Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel," Nature Communications, Nature, vol. 11(1), pages 1-10, December.
    6. Emma B. Hodcroft & Moira Zuber & Sarah Nadeau & Timothy G. Vaughan & Katharine H. D. Crawford & Christian L. Althaus & Martina L. Reichmuth & John E. Bowen & Alexandra C. Walls & Davide Corti & Jesse , 2021. "Spread of a SARS-CoV-2 variant through Europe in the summer of 2020," Nature, Nature, vol. 595(7869), pages 707-712, July.
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    1. Jordan Douglas & David Winter & Andrea McNeill & Sam Carr & Michael Bunce & Nigel French & James Hadfield & Joep Ligt & David Welch & Jemma L. Geoghegan, 2022. "Tracing the international arrivals of SARS-CoV-2 Omicron variants after Aotearoa New Zealand reopened its border," Nature Communications, Nature, vol. 13(1), pages 1-10, December.

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