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Effectiveness of BBIBP-CorV vaccine against severe outcomes of COVID-19 in Abu Dhabi, United Arab Emirates

Author

Listed:
  • Nawal Al Kaabi

    (Sheikh Khalifa Medical City SEHA
    Khalifa University)

  • Abderrahim Oulhaj

    (Khalifa University
    United Arab Emirates University
    Khalifa University)

  • Subhashini Ganesan

    (G42 Healthcare, Masdar City
    IROS (Insights Research Organization & Solutions))

  • Farida Ismail Al Hosani

    (Abu Dhabi Public Health Center – ADPHC)

  • Omer Najim

    (Department of Health (DOH))

  • Halah Ibrahim

    (Khalifa University)

  • Juan Acuna

    (Khalifa University
    Khalifa University)

  • Ahmed R. Alsuwaidi

    (United Arab Emirates University)

  • Ashraf M. Kamour

    (Sheikh Khalifa Medical City SEHA)

  • Ashraf Alzaabi

    (United Arab Emirates University)

  • Badreyya Ahmed Al Shehhi

    (Abu Dhabi Public Health Center – ADPHC)

  • Habiba Al Safar

    (Khalifa University of Science and Technology
    Khalifa University of Science and Technology
    Ministry of Interior)

  • Salah Eldin Hussein

    (Sheikh Khalifa Medical City SEHA)

  • Jehad Saleh Abdalla

    (Sheikh Khalifa Medical City SEHA)

  • Dalal Saeed Naser Al Mansoori

    (Tawam hospital SEHA)

  • Ahmed Abdul Kareem Al Hammadi

    (Tawam hospital SEHA)

  • Mohammed A. Amari

    (Sheikh Khalifa Medical City SEHA)

  • Ahmed Khamis Al Romaithi

    (Sheikh Khalifa Medical City SEHA)

  • Stefan Weber

    (Reference Laboratory for Infectious Diseases (RLID) and Union 71)

  • Santosh Elavalli

    (G42 Healthcare, Masdar City)

  • Islam Eltantawy

    (IROS (Insights Research Organization & Solutions))

  • Noura Khamis Alghaithi

    (Ambulatory Health Services- SEHA)

  • Jumana Nafiz Al Azazi

    (Abu Dhabi Health Services Company- SEHA
    Abu Dhabi Executive Office)

  • Stephen Geoffrey Holt

    (SEHA Kidney Care, SEHA, Abu Dhabi Health Services Company)

  • Mohamed Mostafa

    (Clinical research organization)

  • Rabih Halwani

    (University of Sharjah)

  • Hanif Khalak

    (G42 Healthcare, Masdar City)

  • Wael Elamin

    (G42 Healthcare, Masdar City)

  • Rami Beiram

    (United Arab Emirates University)

  • Walid Zaher

    (Khalifa University
    United Arab Emirates University
    G42 Healthcare, Masdar City
    IROS (Insights Research Organization & Solutions))

Abstract

The effectiveness of the inactivated BBIBP-CorV vaccine against severe COVID-19 outcomes (hospitalization, critical care admission and death due to COVID-19) and its long-term effectiveness have not been well characterized among the general population. We conducted a retrospective cohort study using electronic health records of 3,147,869 adults, of which 1,099,886 vaccinated individuals were matched, in a 1:1 ratio to 1,099,886 unvaccinated persons. A Cox-proportional hazard model with time varying coefficients was used to assess the vaccine effectiveness adjusting for age, sex, comorbidity, ethnicity, and the calendar month of entry into the study. Our analysis showed that the effectiveness was 79.6% (95% CI, 77.7 to 81.3) against hospitalization, 86% (95% CI, 82.2 to 89.0) against critical care admission, and 84.1% (95% CI, 70.8 to 91.3) against death due to COVID-19. The effectiveness against these severe outcomes declined over time indicating the need for booster doses to increase protection against severe COVID-19 outcomes.

Suggested Citation

  • Nawal Al Kaabi & Abderrahim Oulhaj & Subhashini Ganesan & Farida Ismail Al Hosani & Omer Najim & Halah Ibrahim & Juan Acuna & Ahmed R. Alsuwaidi & Ashraf M. Kamour & Ashraf Alzaabi & Badreyya Ahmed Al, 2022. "Effectiveness of BBIBP-CorV vaccine against severe outcomes of COVID-19 in Abu Dhabi, United Arab Emirates," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-30835-1
    DOI: 10.1038/s41467-022-30835-1
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    Cited by:

    1. Marco A. F. Pimentel & Maaz Shaikh & Muna Al Safi & Yousuf Naqvi & Shadab Khan, 2024. "COVID-19 vaccination and major cardiovascular and haematological adverse events in Abu Dhabi: retrospective cohort study," Nature Communications, Nature, vol. 15(1), pages 1-8, December.

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