IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v11y2020i1d10.1038_s41467-020-14327-8.html
   My bibliography  Save this article

Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa

Author

Listed:
  • Brian R. Amman

    (Centers for Disease Control and Prevention)

  • Brian H. Bird

    (University of California)

  • Ibrahim A. Bakarr

    (Njala University)

  • James Bangura

    (University of California
    University of Makeni)

  • Amy J. Schuh

    (Centers for Disease Control and Prevention)

  • Jonathan Johnny

    (Njala University)

  • Tara K. Sealy

    (Centers for Disease Control and Prevention)

  • Immah Conteh

    (Njala University)

  • Alusine H. Koroma

    (Njala University)

  • Ibrahim Foday

    (Njala University)

  • Emmanuel Amara

    (University of Makeni)

  • Abdulai A. Bangura

    (University of Makeni)

  • Aiah A. Gbakima

    (Ministry of Technical and Higher Education)

  • Alexandre Tremeau-Bravard

    (Njala University)

  • Manjunatha Belaganahalli

    (Njala University)

  • Jasjeet Dhanota

    (University of California)

  • Andrew Chow

    (University of California)

  • Victoria Ontiveros

    (University of California)

  • Alexandra Gibson

    (University of California)

  • Joseph Turay

    (University of Makeni)

  • Ketan Patel

    (Centers for Disease Control and Prevention)

  • James Graziano

    (Centers for Disease Control and Prevention)

  • Camilla Bangura

    (Njala University)

  • Emmanuel S. Kamanda

    (Njala University)

  • Augustus Osborne

    (Njala University)

  • Emmanuel Saidu

    (Njala University)

  • Jonathan Musa

    (Njala University)

  • Doris Bangura

    (Njala University)

  • Samuel Maxwell Tom Williams

    (Njala University)

  • Richard Wadsworth

    (Njala University)

  • Mohamed Turay

    (University of Makeni)

  • Lavalie Edwin

    (University of Makeni)

  • Vanessa Mereweather-Thompson

    (University of Makeni)

  • Dickson Kargbo

    (University of Makeni)

  • Fatmata V. Bairoh

    (University of Makeni)

  • Marilyn Kanu

    (University of Makeni)

  • Willie Robert

    (University of Makeni)

  • Victor Lungai

    (University of Makeni)

  • Raoul Emeric Guetiya Wadoum

    (University of Makeni)

  • Moinya Coomber

    (University of Makeni)

  • Osman Kanu

    (University of Makeni)

  • Amara Jambai

    (Ministry of Health and Sanitation)

  • Sorie M. Kamara

    (Ministry of Agriculture and Forestry)

  • Celine H. Taboy

    (Centers for Disease Control and Prevention)

  • Tushar Singh

    (Center for Global Health, Centers for Disease Control and Prevention)

  • Jonna A. K. Mazet

    (University of California)

  • Stuart T. Nichol

    (Centers for Disease Control and Prevention)

  • Tracey Goldstein

    (University of California)

  • Jonathan S. Towner

    (Centers for Disease Control and Prevention)

  • Aiah Lebbie

    (Njala University)

Abstract

Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus aegyptiacus) as a natural reservoir. However, the largest recorded MVD outbreak with the highest case–fatality ratio happened in 2005 in Angola, where direct spillover from bats was not shown. Here, collaborative studies by the Centers for Disease Control and Prevention, Njala University, University of California, Davis USAID-PREDICT, and the University of Makeni identify MARV circulating in ERBs in Sierra Leone. PCR, antibody and virus isolation data from 1755 bats of 42 species shows active MARV infection in approximately 2.5% of ERBs. Phylogenetic analysis identifies MARVs that are similar to the Angola strain. These results provide evidence of MARV circulation in West Africa and demonstrate the value of pathogen surveillance to identify previously undetected threats.

Suggested Citation

  • Brian R. Amman & Brian H. Bird & Ibrahim A. Bakarr & James Bangura & Amy J. Schuh & Jonathan Johnny & Tara K. Sealy & Immah Conteh & Alusine H. Koroma & Ibrahim Foday & Emmanuel Amara & Abdulai A. Ban, 2020. "Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa," Nature Communications, Nature, vol. 11(1), pages 1-9, December.
    • Handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-14327-8
    DOI: 10.1038/s41467-020-14327-8
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-020-14327-8
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-020-14327-8?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Joseph Akoi Boré & Joseph W. S. Timothy & Tom Tipton & Ifono Kekoura & Yper Hall & Grace Hood & Stephanie Longet & Kimberly Fornace & Millimono S. Lucien & Sarah Katarina Fehling & Beatrice K. Koivogu, 2024. "Serological evidence of zoonotic filovirus exposure among bushmeat hunters in Guinea," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    2. Jonathan C. Guito & Shannon G. M. Kirejczyk & Amy J. Schuh & Brian R. Amman & Tara K. Sealy & James Graziano & Jessica R. Spengler & Jessica R. Harmon & David M. Wozniak & Joseph B. Prescott & Jonatha, 2024. "Coordinated inflammatory responses dictate Marburg virus control by reservoir bats," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:11:y:2020:i:1:d:10.1038_s41467-020-14327-8. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.