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A Simulation Approach for the Design of More Sustainable and Resilient Supply Chains in the Pharmaceutical Industry

Author

Listed:
  • Ana Carolina Silva

    (INESC TEC—Instituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal)

  • Catarina Moreira Marques

    (INESC TEC—Instituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal)

  • Jorge Pinho de Sousa

    (INESC TEC—Instituto de Engenharia de Sistemas e Computadores, Tecnologia e Ciência, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal
    Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal)

Abstract

In a world facing unprecedented challenges, such as climate changes and growing social problems, the pharmaceutical industry must ensure that its supply chains are environmentally sustainable and resilient, guaranteeing access to key medications even when faced with unanticipated disruptions or crises. The core goal of this work is to develop an innovative simulation-based approach to support more informed and effective decision making, while establishing reasonable trade-offs between supply chain robustness and resiliency, operational efficiency, and environmental and social concerns. Such a decision-support system will contribute to the development of more resilient and sustainable pharmaceutical supply chains, which are, in general, critical for maintaining access to essential medicines, especially during times of crises or relevant disruptions. The system will help companies to better manage and design their supply chains, providing a valuable tool to achieve higher levels of resilience and sustainability. The study we conducted has two primary contributions that are noteworthy. Firstly, we present a new advanced approach that integrates multiple simulation techniques, allowing for the modeling of highly complex environments. Secondly, we introduce a new conceptual framework that helps to comprehend the interplay between resiliency and sustainability in decision-making processes. These two contributions provide valuable insights into understanding complex systems and can aid in designing more resilient and sustainable systems.

Suggested Citation

  • Ana Carolina Silva & Catarina Moreira Marques & Jorge Pinho de Sousa, 2023. "A Simulation Approach for the Design of More Sustainable and Resilient Supply Chains in the Pharmaceutical Industry," Sustainability, MDPI, vol. 15(9), pages 1-23, April.
    • Handle: RePEc:gam:jsusta:v:15:y:2023:i:9:p:7254-:d:1134008
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    References listed on IDEAS

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    1. Dmitry Ivanov, 2018. "Revealing interfaces of supply chain resilience and sustainability: a simulation study," International Journal of Production Research, Taylor & Francis Journals, vol. 56(10), pages 3507-3523, May.
    2. Fahimnia, Behnam & Jabbarzadeh, Armin, 2016. "Marrying supply chain sustainability and resilience: A match made in heaven," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 91(C), pages 306-324.
    3. Xinqiu Zhu & Yenchun Jim Wu, 2022. "How Does Supply Chain Resilience Affect Supply Chain Performance? The Mediating Effect of Sustainability," Sustainability, MDPI, vol. 14(21), pages 1-19, November.
    4. Saheeb Ahmed Kayani & Salman Sagheer Warsi & Raja Awais Liaqait, 2023. "A Smart Decision Support Framework for Sustainable and Resilient Supplier Selection and Order Allocation in the Pharmaceutical Industry," Sustainability, MDPI, vol. 15(7), pages 1-30, March.
    5. Klaus R.N. Hansen & Martin Grunow, 2015. "Modelling ramp-up curves to reflect learning: improving capacity planning in secondary pharmaceutical production," International Journal of Production Research, Taylor & Francis Journals, vol. 53(18), pages 5399-5417, September.
    6. Shashi & Piera Centobelli & Roberto Cerchione & Myriam Ertz, 2020. "Managing supply chain resilience to pursue business and environmental strategies," Business Strategy and the Environment, Wiley Blackwell, vol. 29(3), pages 1215-1246, March.
    7. Pinyarat Sirisomboonsuk & James Burns, 2023. "Sustainability in Supply Chains through Rapid Capacity Increases and Minimized Disruptions," Sustainability, MDPI, vol. 15(7), pages 1-17, March.
    8. Lücker, Florian & Seifert, Ralf W., 2017. "Building up Resilience in a Pharmaceutical Supply Chain through Inventory, Dual Sourcing and Agility Capacity," Omega, Elsevier, vol. 73(C), pages 114-124.
    9. Henry, Devanandham & Emmanuel Ramirez-Marquez, Jose, 2012. "Generic metrics and quantitative approaches for system resilience as a function of time," Reliability Engineering and System Safety, Elsevier, vol. 99(C), pages 114-122.
    10. Patrycja Hoffa-Dabrowska & Katarzyna Grzybowska, 2020. "Simulation Modeling of the Sustainable Supply Chain," Sustainability, MDPI, vol. 12(15), pages 1-15, July.
    11. Marta Negri & Enrico Cagno & Claudia Colicchia & Joseph Sarkis, 2021. "Integrating sustainability and resilience in the supply chain: A systematic literature review and a research agenda," Business Strategy and the Environment, Wiley Blackwell, vol. 30(7), pages 2858-2886, November.
    12. Armin Jabbarzadeh & Behnam Fahimnia & Fatemeh Sabouhi, 2018. "Resilient and sustainable supply chain design: sustainability analysis under disruption risks," International Journal of Production Research, Taylor & Francis Journals, vol. 56(17), pages 5945-5968, September.
    13. Antonio Zavala-Alcívar & María-José Verdecho & Juan-José Alfaro-Saiz, 2020. "A Conceptual Framework to Manage Resilience and Increase Sustainability in the Supply Chain," Sustainability, MDPI, vol. 12(16), pages 1-38, August.
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