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A Non-Mixture Cure Model for Right-Censored Data with Fréchet Distribution

Author

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  • Durga H. Kutal

    (Department of Mathematical Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA
    Durga H. Kutal currently is a visiting assistant professor at Wake Forest University, NC, USA.)

  • Lianfen Qian

    (Department of Mathematical Sciences, Florida Atlantic University, Boca Raton, FL 33431, USA
    Lianfen Qian is a distinguished guest professor of Wenzhou University, Wenzhou, China.)

Abstract

This paper considers a non-mixture cure model for right-censored data. It utilizes the maximum likelihood method to estimate model parameters in the non-mixture cure model. The simulation study is based on Fréchet susceptible distribution to evaluate the performance of the method. Compared with Weibull and exponentiated exponential distributions, the non-mixture Fréchet distribution is shown to be the best in modeling a real data on allogeneic marrow HLA-matched donors and ECOG phase III clinical trial e1684 data.

Suggested Citation

  • Durga H. Kutal & Lianfen Qian, 2018. "A Non-Mixture Cure Model for Right-Censored Data with Fréchet Distribution," Stats, MDPI, vol. 1(1), pages 1-13, November.
  • Handle: RePEc:gam:jstats:v:1:y:2018:i:1:p:13-188:d:183187
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    References listed on IDEAS

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    1. Patilea, Valentin & Van Keilegom, Ingrid, 2017. "A general approach for cure models in survival analysis," LIDAM Discussion Papers ISBA 2017008, Université catholique de Louvain, Institute of Statistics, Biostatistics and Actuarial Sciences (ISBA).
    2. Yingwei Peng & Keith B. G. Dear, 2000. "A Nonparametric Mixture Model for Cure Rate Estimation," Biometrics, The International Biometric Society, vol. 56(1), pages 237-243, March.
    3. Carvalho Lopes, Celia Mendes & Bolfarine, Heleno, 2012. "Random effects in promotion time cure rate models," Computational Statistics & Data Analysis, Elsevier, vol. 56(1), pages 75-87, January.
    4. Joseph G. Ibrahim & Ming-Hui Chen & Debajyoti Sinha, 2001. "Bayesian Semiparametric Models for Survival Data with a Cure Fraction," Biometrics, The International Biometric Society, vol. 57(2), pages 383-388, June.
    5. Liu, Hao & Shen, Yu, 2009. "A Semiparametric Regression Cure Model for Interval-Censored Data," Journal of the American Statistical Association, American Statistical Association, vol. 104(487), pages 1168-1178.
    6. Tsodikov A.D. & Ibrahim J.G. & Yakovlev A.Y., 2003. "Estimating Cure Rates From Survival Data: An Alternative to Two-Component Mixture Models," Journal of the American Statistical Association, American Statistical Association, vol. 98, pages 1063-1078, January.
    7. Els Goetghebeur & Louise Ryan, 2000. "Semiparametric Regression Analysis of Interval-Censored Data," Biometrics, The International Biometric Society, vol. 56(4), pages 1139-1144, December.
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    Cited by:

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