IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v7y2010i5p1872-1888d8091.html
   My bibliography  Save this article

Molecular Basis and Current Treatment for Alcoholic Liver Disease

Author

Listed:
  • Alejandra Miranda-Mendez

    (Institute for Molecular Biology in Medicine and Gene Therapy, University of Guadalajara, Jalisco 44281, Mexico)

  • Alejandro Lugo-Baruqui

    (Institute for Molecular Biology in Medicine and Gene Therapy, University of Guadalajara, Jalisco 44281, Mexico
    OPD Hospital Civil de Guadalajara, Jalisco 44340, Mexico)

  • Juan Armendariz-Borunda

    (Institute for Molecular Biology in Medicine and Gene Therapy, University of Guadalajara, Jalisco 44281, Mexico
    OPD Hospital Civil de Guadalajara, Jalisco 44340, Mexico)

Abstract

Alcohol use disorders and alcohol dependency affect millions of individuals worldwide. The impact of these facts lies in the elevated social and economic costs. Alcoholic liver disease is caused by acute and chronic exposure to ethanol which promotes oxidative stress and inflammatory response. Chronic consumption of ethanol implies liver steatosis, which is the first morphological change in the liver, followed by liver fibrosis and cirrhosis. This review comprises a broad approach of alcohol use disorders, and a more specific assessment of the pathophysiologic molecular basis, and genetics, as well as clinical presentation and current modalities of treatment for alcoholic liver disease.

Suggested Citation

  • Alejandra Miranda-Mendez & Alejandro Lugo-Baruqui & Juan Armendariz-Borunda, 2010. "Molecular Basis and Current Treatment for Alcoholic Liver Disease," IJERPH, MDPI, vol. 7(5), pages 1-17, April.
    • Handle: RePEc:gam:jijerp:v:7:y:2010:i:5:p:1872-1888:d:8091
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/7/5/1872/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/7/5/1872/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Salvador Manzo-Avalos & Alfredo Saavedra-Molina, 2010. "Cellular and Mitochondrial Effects of Alcohol Consumption," IJERPH, MDPI, vol. 7(12), pages 1-24, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:7:y:2010:i:5:p:1872-1888:d:8091. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.