Internalization of Near-Infrared Fluorescent Dyes within Isolated Leukocyte Populations
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- Atsushi Miyawaki & Juan Llopis & Roger Heim & J. Michael McCaffery & Joseph A. Adams & Mitsuhiko Ikura & Roger Y. Tsien, 1997. "Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin," Nature, Nature, vol. 388(6645), pages 882-887, August.
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Scientists have expressed continued interest in the development of microsensor technology that can indicate toxicity that occurs within a cell after a chemical challenge. One of the more useful approaches of microsensor technology is the application of fluorescent spectroscopy to indicate early-stage injury with optimal specificity and decreased background interference. If the toxicity is detected during the early onset period of injury; then the probability for therapeutic recovery is promising;Statistics
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