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Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients

Author

Listed:
  • Miriã C. Oliveira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Larissa R. Alves

    (Faculty of Medicine, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil
    Health Sciences Graduate Program, Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01224-001, SP, Brazil)

  • Juliana M. P. Soares

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Shayra K. A. Souza

    (Scientific Initiation Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Bruna M. R. Silva

    (Scientific Initiation Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Adriano L. Fonseca

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Carlos H. M. Silva

    (Faculty of Medicine, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil
    Health Sciences Graduate Program, Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01224-001, SP, Brazil)

  • Claudia S. Oliveira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Rodolfo P. Vieira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Deise A. A. P. Oliveira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Iransé Oliveira-Silva

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Rodrigo F. Oliveira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Luciana M. M. Sampaio

    (Rehabilitation Sciences, Graduate Program, Nove de Julho University (UNINOVE), São Paulo 01504-001, SP, Brazil)

  • Vinicius Maldaner

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Dante B. Santos

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

  • Renata K. Palma

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil
    Facultad de Ciencias de la Salud de Manresa, Universitat de Vic-Universitat Central de Catalunya (UVic-UCC), 08242 Manresa, Spain)

  • Sergio R. Nacif

    (Health Sciences Graduate Program, Institute of Medical Assistance to State Public Servants (IAMSPE), Av. Ibirapuera, 981, São Paulo 04029-000, SP, Brazil)

  • Giuseppe Insalaco

    (Institute of Translational Pharmacology, National Research Council of Italy (CNR), 90146 Palermo, Italy)

  • Luís V. F. Oliveira

    (Human Movement and Rehabilitation Graduate Program, Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil)

Abstract

Background: COVID-19 mainly affects the respiratory system, although its manifestations are multisystemic. We are increasingly recognizing complications that present after the acute phase, which are associated with impaired functional status and health-related quality of life (HRQoL). The objective was to assess the functional status and HRQoL of patients with post-COVID-19. Methods: This was a cross-sectional study involving individuals affected by COVID-19 who had persistent symptoms for one month after the acute phase of the disease. Functional status was measured with the six-minute walk test (6MWT), the Fatigue Severity Scale (FSS), the Medical Research Council (MRC) Dyspnea Scale, and the Post-COVID-19 Functional Status Scale (PCFS). HRQoL was confirmed with the Short-Form Health Survey 36 (SF-36). Results: We included 123 patients; 73 (59.35%) were male, with a mean age of 49.17 ± 13.48 years and a body mass index of 31.02 ± 6.56 stratified into three groups: the not-recovered group (NRG = 23), the ward-recovered group (WHG = 60), and the intensive-care-unit group (ICUG = 40). The main symptoms were muscle weakness (74.17%) and dyspnea (68.33%). The predicted distances for the 6MWT were missed by 12.83% by the GNR group, 20.21% by the GNR group, and 28.82% by the UGCI group. The MRC dyspnea scale had a mean value of less than 3, and the FSS scale had a mean value of over 4, indicating considerable fatigue. In the PCFS scale, a significant difference was observed ( p < 0.0005), while in the SF-36, all HRQoL domains were compromised. Conclusion: Post-COVID-19 patients involved in this study showed a significant decline in functional status and an impairment of HRQoL.

Suggested Citation

  • Miriã C. Oliveira & Larissa R. Alves & Juliana M. P. Soares & Shayra K. A. Souza & Bruna M. R. Silva & Adriano L. Fonseca & Carlos H. M. Silva & Claudia S. Oliveira & Rodolfo P. Vieira & Deise A. A. P, 2025. "Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients," IJERPH, MDPI, vol. 22(3), pages 1-17, February.
    • Handle: RePEc:gam:jijerp:v:22:y:2025:i:3:p:338-:d:1599638
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    References listed on IDEAS

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    1. Rodrigo Núñez-Cortés & Constanza Malhue-Vidal & Florencia Gath & Gonzalo Valdivia-Lobos & Rodrigo Torres-Castro & Carlos Cruz-Montecinos & Francisco M. Martinez-Arnau & Sofía Pérez-Alenda & Rubén Lópe, 2022. "The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up," IJERPH, MDPI, vol. 19(12), pages 1-9, June.
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