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Impact of COVID-19 Infection on Health-Related Quality of Life in the Japanese Population: A Large Health-Insurance-Based Database Study

Author

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  • Tomoko Kobayashi

    (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan)

  • Chikara Miyaji

    (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
    Health Service Center, Okayama University, 2-1-1 Tsushimanaka, Kita-ku, Okayama 700-0082, Japan)

  • Hiroshi Habu

    (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
    Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Yoshida-konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan)

  • Yoshiharu Horie

    (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan)

  • Soshi Takao

    (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan)

Abstract

Evidence for acute or long-term coronavirus disease 2019 (COVID-19) infection is relatively limited. We aimed to evaluate the impact of COVID-19 infection on health-related quality of life (HRQoL) in the Japanese population. Eligible study participants were 13,365 employees and their dependents who answered questionnaires at baseline and 18 months later and who had at least 6 months of continuous enrolment before and after baseline. Of the 711 study participants who developed COVID-19 infection, 29.0% reported a decline in HRQoL, whereas 25.2% of uninfected participants reported a decline. The adjusted odds ratios (95% confidence intervals) for the association between COVID-19 infection and declines in HRQoL in the age categories of less than 30 years, 30s, 40s, 50s, and 60 years or higher were 0.54 (0.15–1.92), 1.70 (1.03–2.81), 1.14 (0.82–1.57), 1.05 (0.77–1.42), and 0.87 (0.46–1.64), respectively. This study demonstrates a differential association between COVID-19 infection and declines in HRQoL by age group. A 1.7-fold increase in the odds of negative changes in HRQoL was observed in only those in their 30s. Further studies are needed to elucidate differences in the impact of COVID-19 infection on HRQoL between younger people such as those in their 30s and the older population.

Suggested Citation

  • Tomoko Kobayashi & Chikara Miyaji & Hiroshi Habu & Yoshiharu Horie & Soshi Takao, 2024. "Impact of COVID-19 Infection on Health-Related Quality of Life in the Japanese Population: A Large Health-Insurance-Based Database Study," IJERPH, MDPI, vol. 21(2), pages 1-10, February.
    • Handle: RePEc:gam:jijerp:v:21:y:2024:i:2:p:217-:d:1338042
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    References listed on IDEAS

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