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Developmental Trajectories and Predictors of Incident Dementia among Elderly Taiwanese People: A 14-Year Longitudinal Study

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  • Yen-Chun Fan

    (School of Public Health, College of Public Health, Taipei Medical University, Taipei 110301, Taiwan
    Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan)

  • Sheng-Feng Lin

    (School of Public Health, College of Public Health, Taipei Medical University, Taipei 110301, Taiwan
    Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan
    Department of Emergency Medicine, Taipei Medical University Hospital, Taipei 110301, Taiwan)

  • Chia-Chi Chou

    (Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei 100025, Taiwan
    School of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
    Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung 204201, Taiwan)

  • Chyi-Huey Bai

    (School of Public Health, College of Public Health, Taipei Medical University, Taipei 110301, Taiwan
    Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan
    Nutrition Research Center, Taipei Medical University Hospital, Taipei 110301, Taiwan)

Abstract

The aim of this study was to identify dementia trajectories and their associated predictors among elderly Taiwanese people over a 14-year period using a nationwide representative longitudinal study. This retrospective cohort study was performed using the National Health Insurance Research Database. Group-based trajectory modeling (GBTM) was used to distinguish the specific trajectory groups of incident dementia during 2000–2013. All 42,407 patients were classified by GBTM to identify the trajectory of incident dementia, which included high- ( n = 11,637, 29.0%), moderate- ( n = 19,036, 44.9%), and low-incidence ( n = 11,734, 26.1%) groups. Those diagnosed with hypertension (adjusted odds ratio [aOR] = 1.43; 95% confidence interval [CI] = 1.35–1.52), stroke (aOR = 1.45, 95% CI = 1.31–1.60), coronary heart disease (aOR = 1.29, 95% CI = 1.19–1.39), heart failure (aOR = 1.62, 95% CI = 1.36–1.93), and chronic obstructive pulmonary disease (aOR = 1.10, 95% CI = 1.02–1.18) at baseline revealed tendencies to be classified into high-incidence groups in dementia risk. The results from a 14-year longitudinal study identified three distinct trajectories of incident dementia among elderly Taiwanese people: patients with cardiovascular disease risk factors and cardiovascular disease events tended to be classified into high-incidence dementia groups. Early detection and management of these associated risk factors in the elderly may prevent or delay the deterioration of cognitive decline.

Suggested Citation

  • Yen-Chun Fan & Sheng-Feng Lin & Chia-Chi Chou & Chyi-Huey Bai, 2023. "Developmental Trajectories and Predictors of Incident Dementia among Elderly Taiwanese People: A 14-Year Longitudinal Study," IJERPH, MDPI, vol. 20(4), pages 1-11, February.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:4:p:3065-:d:1063483
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    References listed on IDEAS

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    1. Alison Abbott, 2011. "Dementia: A problem for our age," Nature, Nature, vol. 475(7355), pages 2-4, July.
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